大脑中记忆储存的表观遗传学。

Cellscience Pub Date : 2010-07-01

R Ryley Parrish, Swati Gupta, Farah D Lubin

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摘要

表观遗传学被认为是一种参与长期记忆编码的分子机制。特别是DNA甲基化，一种被认为在细胞分化后是静态的表观遗传机制，被认为是长期记忆储存过程中的动态转录调节机制。最近发表在《自然神经科学》(Nature Neuroscience)杂志上的研究结果探索了大脑皮层内稳定的DNA甲基化变化有助于记忆维持的可能性。

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The epigenetics of memory storage in the brain.

Epigenetics has been proposed as a molecular mechanism involved in encoding long-term memories. Specifically DNA methylation, an epigenetic mechanism thought to be static following cell differentiation, has been implicated as a dynamic transcription regulatory mechanism underlying the process of longterm memory storage. Now recent findings published in Nature Neuroscience explore the possibility that stable DNA methylation changes within the cortex contributes to memory maintenance.

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Cellscience

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