中国一名康复患者粪便标本中SARS-CoV-2的发现和全基因组表征

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2021-09-01 Epub Date: 2021-09-17 DOI:10.33073/pjm-2021-029
Yongdong Li, Y I Chen, Hongxia Ni, B O Yi, Dandan Zhang, Jianing Zhang, Wenjing Wang, Yuhui Liu, Suli Jiao, Guozhang Xu, Weidong Qian
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引用次数: 1

摘要

采用定量反转录PCR (qRT-PCR)和基因组测序相结合的方法,在一名康复患者的粪便标本中发现了SARS-CoV-2。患者在康复后至少在另外15天的粪便标本中呈病毒阳性,而呼吸道标本呈阴性。在康复患者的粪便样本中发现了SARS-CoV-2的全基因组,这是一个警告,即病毒在呼吸道被清除后,不能排除病毒通过粪-口途径传播的潜在模式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Discovery and Full Genome Characterization of SARS-CoV-2 in Stool Specimen from a Recovered Patient, China.

SARS-CoV-2 was found in a recovered patient's stool specimen by combining quantitative reverse transcription PCR (qRT-PCR) and genome sequencing. The patient was virus positive in stool specimens for at least an additional 15 days after he was recovered, whereas respiratory tract specimens were negative. The discovery of the complete genome of SARS-CoV-2 in the stool sample of the recovered patient demonstrates a cautionary warning that the potential mode of the virus transmission cannot be excluded through the fecal-oral route after viral clearance in the respiratory tract.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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