通过染色体拷贝数异质性预测癌症患者的生存。

IF 2.6 Q3 ONCOLOGY Molecular and Cellular Oncology Pub Date : 2021-08-03 eCollection Date: 2021-01-01 DOI:10.1080/23723556.2021.1949956
Tom Van Den Bosch, Erik van Dijk, Louis Vermeulen, Daniël M Miedema
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引用次数: 1

摘要

我们最近介绍了一种从单一拷贝数测量中得出肿瘤内异质性(ITH)的方法。这种方法对患者的生存进行分层,并可能有助于识别具有临床相关性的低危患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Predicting survival of cancer patients by chromosomal copy number heterogeneity.
ABSTRACT We recently introduced a method to derive intra-tumor heterogeneity (ITH) from a single copy number measurement. This method stratifies patients for survival and could potentially help to identify low and high-risk patients with clinical relevance.
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来源期刊
Molecular and Cellular Oncology
Molecular and Cellular Oncology Biochemistry, Genetics and Molecular Biology-Cancer Research
CiteScore
3.20
自引率
0.00%
发文量
18
期刊介绍: For a long time, solid neoplasms have been viewed as relatively homogeneous entities composed for the most part of malignant cells. It is now clear that tumors are highly heterogeneous structures that evolve in the context of intimate interactions between cancer cells and endothelial, stromal as well as immune cells. During the past few years, experimental and clinical oncologists have witnessed several conceptual transitions of this type. Molecular and Cellular Oncology (MCO) emerges within this conceptual framework as a high-profile forum for the publication of fundamental, translational and clinical research on cancer. The scope of MCO is broad. Submissions dealing with all aspects of oncogenesis, tumor progression and response to therapy will be welcome, irrespective of whether they focus on solid or hematological neoplasms. MCO has gathered leading scientists with expertise in multiple areas of cancer research and other fields of investigation to constitute a large, interdisciplinary, Editorial Board that will ensure the quality of articles accepted for publication. MCO will publish Original Research Articles, Brief Reports, Reviews, Short Reviews, Commentaries, Author Views (auto-commentaries) and Meeting Reports dealing with all aspects of cancer research.
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