SARS-CoV-2疫苗(科兴®)后急性哮喘加重1例报告

IF 3 Q2 MEDICINE, RESEARCH & EXPERIMENTAL Medical Gas Research Pub Date : 2022-04-01 DOI:10.4103/2045-9912.326003

Fatih Uzer, Aykut Cilli

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引用次数: 10

摘要

一名76岁女性接种了严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)疫苗(CoronaVac, Sinovac®，北京，中国)，随后出现胸部不适。接种疫苗1天后进行的计算机断层扫描显示双肺多发浸润，双肺野可见磨玻璃影。她的指尖氧饱和度为81%，体格检查有广泛的喘息。根据这些发现，患者住院治疗，初步诊断为SARS-CoV-2疫苗引起的药物性肺炎和急性哮喘加重。住院期间给予全身类固醇40 mg/d，沙丁胺醇雾化4次/d，吸氧2 L/min，莫西沙星静脉注射400 mg/d，连续5天。一个月后，胸部计算机断层扫描显示先前的发现几乎完全恢复。

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Acute asthma exacerbation after SARS-CoV-2 vaccine (Sinovac®): a case report.

A 76-year-old female received a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine (CoronaVac, Sinovac^®, Beijing, China) and subsequently experienced chest discomfort. A computed tomography performed 1 day after vaccination showed multiple infiltrations in both lungs and ground-glass shadows in both lung fields. Her fingertip oxygen saturation was 81% and there was widespread wheezing on physical examination. Based on these findings, the patient was hospitalized with a preliminary diagnosis of drug-induced pneumonitis and acute asthma exacerbation due to a SARS-CoV-2 vaccine. During her hospitalization, 40 mg/d systemic steroid, 4 times a day salbutamol nebulized, 2 L/min inhaled oxygen therapy and 400 mg/d moxifloxacin intravenous were administered for 5 days. One month later, the thorax computed tomography scan revealed that the previous findings were almost completely regressed.

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来源期刊

Medical Gas Research MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

5.10

自引率

13.80%

发文量

期刊介绍： Medical Gas Research is an open access journal which publishes basic, translational, and clinical research focusing on the neurobiology as well as multidisciplinary aspects of medical gas research and their applications to related disorders. The journal covers all areas of medical gas research, but also has several special sections. Authors can submit directly to these sections, whose peer-review process is overseen by our distinguished Section Editors: Inert gases - Edited by Xuejun Sun and Mark Coburn, Gasotransmitters - Edited by Atsunori Nakao and John Calvert, Oxygen and diving medicine - Edited by Daniel Rossignol and Ke Jian Liu, Anesthetic gases - Edited by Richard Applegate and Zhongcong Xie, Medical gas in other fields of biology - Edited by John Zhang. Medical gas is a large family including oxygen, hydrogen, carbon monoxide, carbon dioxide, nitrogen, xenon, hydrogen sulfide, nitrous oxide, carbon disulfide, argon, helium and other noble gases. These medical gases are used in multiple fields of clinical practice and basic science research including anesthesiology, hyperbaric oxygen medicine, diving medicine, internal medicine, emergency medicine, surgery, and many basic sciences disciplines such as physiology, pharmacology, biochemistry, microbiology and neurosciences. Due to the unique nature of medical gas practice, Medical Gas Research will serve as an information platform for educational and technological advances in the field of medical gas.