{"title":"在拟除虫菊酯抗性烟甲虫株中发现钠通道突变(T929I和F1534S)。","authors":"Naoto Fukazawa, Ryota Takahashi, Hinako Matsuda, Yuya Mikawa, Toshiyuki Suzuki, Tomohiro Suzuki, Shoji Sonoda","doi":"10.1584/jpestics.D21-033","DOIUrl":null,"url":null,"abstract":"<p><p>RNA-seq data analysis of cigarette beetle (<i>Lasioderma serricorne</i>) strains having different sensitivities to pyrethroids identified sodium channel mutations in strains showing pyrethroid resistance: the T929I and F1534S mutations. These results suggest that reduced sensitivity of the sodium channel confers the pyrethroid resistance of <i>L. serricorne</i>. Results also showed that the F1534S mutation mostly occurred concurrently with the T929I mutation. The functional relation between both mutations for pyrethroid resistance is discussed.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"46 4","pages":"360-365"},"PeriodicalIF":1.5000,"publicationDate":"2021-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2a/6a/jps-46-4-D21-033.PMC8640701.pdf","citationCount":"0","resultStr":"{\"title\":\"Sodium channel mutations (T929I and F1534S) found in pyrethroid-resistant strains of the cigarette beetle, <i>Lasioderma serricorne</i> (Coleoptera: Anobiidae).\",\"authors\":\"Naoto Fukazawa, Ryota Takahashi, Hinako Matsuda, Yuya Mikawa, Toshiyuki Suzuki, Tomohiro Suzuki, Shoji Sonoda\",\"doi\":\"10.1584/jpestics.D21-033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>RNA-seq data analysis of cigarette beetle (<i>Lasioderma serricorne</i>) strains having different sensitivities to pyrethroids identified sodium channel mutations in strains showing pyrethroid resistance: the T929I and F1534S mutations. These results suggest that reduced sensitivity of the sodium channel confers the pyrethroid resistance of <i>L. serricorne</i>. Results also showed that the F1534S mutation mostly occurred concurrently with the T929I mutation. The functional relation between both mutations for pyrethroid resistance is discussed.</p>\",\"PeriodicalId\":16712,\"journal\":{\"name\":\"Journal of Pesticide Science\",\"volume\":\"46 4\",\"pages\":\"360-365\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2021-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2a/6a/jps-46-4-D21-033.PMC8640701.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pesticide Science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1584/jpestics.D21-033\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENTOMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pesticide Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1584/jpestics.D21-033","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENTOMOLOGY","Score":null,"Total":0}
Sodium channel mutations (T929I and F1534S) found in pyrethroid-resistant strains of the cigarette beetle, Lasioderma serricorne (Coleoptera: Anobiidae).
RNA-seq data analysis of cigarette beetle (Lasioderma serricorne) strains having different sensitivities to pyrethroids identified sodium channel mutations in strains showing pyrethroid resistance: the T929I and F1534S mutations. These results suggest that reduced sensitivity of the sodium channel confers the pyrethroid resistance of L. serricorne. Results also showed that the F1534S mutation mostly occurred concurrently with the T929I mutation. The functional relation between both mutations for pyrethroid resistance is discussed.
期刊介绍：
The Journal of Pesticide Science publishes the results of original research regarding the chemistry and biochemistry of pesticides including bio-based materials. It also covers their metabolism, toxicology, environmental fate and formulation.
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