龋齿的遗传性:双胞胎研究。

Q2 Dentistry Monographs in Oral Science Pub Date : 2021-01-01 Epub Date: 2022-01-25 DOI:10.1159/000520768
Alexandre Rezende Vieira
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引用次数: 2

摘要

对双胞胎的研究是一个强大的工具,可以推断遗传变异对特定特征或疾病的存在和贡献程度。将同卵或同卵双胞胎与异卵双胞胎进行比较的能力允许将基因组DNA 100%相同的个体与只有50%相同的个体进行直接比较,假设这些个体处于相同的环境中。在龋齿的情况下,环境是相同的父母,在同一个屋檐下,有相同的饮食,口腔卫生习惯,文化和生活方式。这些数据一致表明,人群中龋齿变异的相关比例是由遗传引起的。
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Heritability of Dental Caries: Twin Studies.

The study of twins is a powerful tool to infer the presence and amount of contribution of genetic variation to a particular trait or disease. The ability to compare identical or monozygotic twins with dizygotic twins permits the direct comparison of pairs of individuals that share 100% of their genomic DNA with pairs that share only 50%, with the assumption that these pairs are under the same environment. In the case of dental caries, the environment is same parents, under the same roof, with the same diet, oral hygiene habits, culture, and lifestyle. These data have consistently suggested that a relevant proportion of the variation of dental caries in populations is due to genetics.

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来源期刊
Monographs in Oral Science
Monographs in Oral Science Medicine-Medicine (all)
CiteScore
3.70
自引率
0.00%
发文量
21
期刊介绍: For two decades, ‘Monographs in Oral Science’ has provided a source of in-depth discussion of selected topics in the sciences related to stomatology. Senior investigators are invited to present expanded contributions in their fields of special expertise. The topics chosen are those which have generated a long-standing interest, and on which new conceptual insights or innovative biotechnology are making considerable impact. Authors are selected on the basis of having made lasting contributions to their chosen field and their willingness to share their findings with others.
期刊最新文献
Chapter 8: Risk Assessment: Considerations for Coronal Caries. Chapter 9.4: Operative Treatment and Monitoring of Coronal Caries in Daily Practice. Chapter 9.3: Current Concepts of Caries Removal in Daily Practice. Chapter 9.1: The Use of Fluorides in the Control of Coronal Caries. Chapter 6: Diagnostic Considerations regarding Coronal Caries.
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