小丑鼻:罕见的下咽癌转移。

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-08-01 Epub Date: 2022-01-05 DOI:10.1177/01455613211069349
Pedro Lopes Alexandre, Ricardo Matos, Ana Marques, Helena Silveira, Pedro Santos Marques, Carla Pinto Moura
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引用次数: 0

摘要

头颈部鳞状细胞癌的皮肤转移并不常见,而位于鼻尖的转移则格外罕见。一名曾接受过下咽鳞状细胞癌手术和化疗的患者,鼻尖出现了几个红色结节状皮肤病变。活检显示原发肿瘤已发生皮肤转移。鉴于其外观和位置,这种表现曾被描述为 "小丑鼻子"。尽管皮肤病变的位置并不常见,但仍应怀疑其为恶性肿瘤,尤其是曾确诊为癌症的患者。临床医生必须意识到,头颈部癌症转移可表现为 "小丑鼻子"。
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Clown Nose: A Rare Hypopharyngeal Cancer Metastasis.

Cutaneous metastases from squamous cell carcinomas of the head and neck region are uncommon, and their location at the nasal tip is exceptionally rare. A patient, previously treated with surgery and chemoradiation for a hypopharyngeal squamous cell carcinoma, developed several red nodular skin lesions at the nasal tip. Biopsy revealed cutaneous metastasis from the primary tumor. This manifestation was previously described as a "clown nose," given their appearance and location. Skin lesions should raise suspicion of malignancy, despite their location at uncommon places, particularly in patients with previous diagnosed cancer. Clinicians must be aware that metastases from head and neck cancer can present as a "clown nose."

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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