Deborah K Erhart, Vera Bracknies, Susanne Lutz-Schuhbauer, Sonja Wigand, Hayrettin Tumani
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The special role of CXCL13 in Lyme neuroborreliosis: a case report.
The diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, encephalomyelitis, encephalopathy and peripheral neuropathy. We report on a patient presenting with basal leptomeningoencephalitis associated with vasculopathy where the chemokine CXCL13 in cerebrospinal fluid played an important diagnostic role.