成人腹膜结核和HIV感染:洛美(多哥)32例。

O Bouglouga, A Bagny, M A Djibril, L M Lawson-Ananissoh, F M'ba, D Redah, A Agbetra
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引用次数: 0

摘要

这项前瞻性研究的目的是描述一系列在多哥洛美接受36个月腹膜结核治疗的成年艾滋病毒感染患者。共纳入32例。患者平均年龄为38岁(20 - 69岁)。男女性别比为0.52。所有病例均有腹水伴发热。10.6%的腹水为渗出性,93.7%的腹水为淋巴细胞性。27例患者分离出腹膜结核,15.6%的患者伴有胸膜受累,75%的患者伴有血液学受累,21.9%的患者伴有肝脏受累。患者对治疗反应不佳,预后不利,死亡率为12.5%。HIV感染极大地改变了腹膜结核的流行病学、临床和治疗概况。
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[Peritoneal tuberculosis and HIV infection in adults: 32 cases in Lome (Togo)].

The purpose of this prospective study is to describe a series of adult HIV-infected patients treated for peritoneal tuberculosis over a 36-month period in Lome, Togo. A total of 32 cases were included. Mean patient age was 38 years (range, 20 to 69). The M/F sex ratio was 0.52. Ascites with fever was observed in all cases. Ascitic fluid was exsudative in 10.6% of cases and lymphocytic in 93.7%. Peritoneal tuberculosis was isolated in 27 patients, associated with pleural involvement in 15.6 % of cases, hematological in 75% and hepatic in 21.9%. Patients responded poorly to therapy and prognosis was unfavorable with a mortality rate of 12.5%. HIV infection substantially alters the epidemiological, clinical and therapeutic profile of peritoneal tuberculosis.

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