在巴马科rodolpher - m rieux实验室,通过糖化血红蛋白检测D-10®(Biorad)和Minicap Flex穿刺®(Sebia)生化系统监测血糖平衡

IF 0.4 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY Annales de biologie clinique Pub Date : 2022-06-30 DOI:10.1684/abc.2022.1738
Aboubacar Dit Tietie Bissan, Casimir Kletigui Dembélé, Djibril Coulibaly, Yaya Goïta, Djambatolom Saidou Tolo, Boubacar Mohammed, Asmaou Soumaré, Madiné Tall, Lassana Gadi Timbiné, Bakary Cissé, Bourèma Kouriba
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引用次数: 0

摘要

本研究旨在确定D-10®和Minicap Flex穿刺®结果的一致性,以及糖化血红蛋白检测中血红蛋白变异的影响。所有的样品都是并行分析的。使用Bland和Altman图评估这些方法之间的一致性。我们共采集了166份样本。在整个研究人群和血红蛋白变异的患者中,Bland和Altman图显示了值之间的良好一致性(分别为0.21%和0.29%)以及显著相关性(p < 0.001)。我们的结果与Kesso Barry等人的发现不同。这一差异可以用我们研究人群中异常血红蛋白S和C的高患病率(39.2%)来解释。尽管两种方法之间有很好的一致性,但结果不允许我们确认两种系统在糖尿病患者和血红蛋白变异携带者之间的可转移性。
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Monitoring of glycemic balance by glycated hemoglobin assay on D-10® (Biorad) and Minicap Flex Piercing® (Sebia) biochemical systems at the Rodolph-Mérieux Laboratory in Bamako

This study aims to determine the concordance of results between D-10® and Minicap Flex Piercing® and the impact of the presence of hemoglobin variants in the glycated hemoglobin assay. All the samples were assayed in parallel. The agreement between these methods was assessed using the Bland and Altman plot. We collected a total of 166 samples. In the entire study population and in patients with a hemoglobin variant, the Bland and Altman graph showed good agreement between the values (for respective biases of 0.21% and 0.29%) as well as a significant correlation (p < 0.001). Our results differ from those found by Kesso Barry et al. This difference can be explained by the high prevalence of patients with abnormal hemoglobins S and C (39.2 %) in our study population. Despite a good agreement between the methods, the results do not allow us to confirm a transferability between the two systems in diabetics and carriers of hemoglobin variants.

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来源期刊
Annales de biologie clinique
Annales de biologie clinique 医学-医学:研究与实验
CiteScore
0.80
自引率
20.00%
发文量
53
审稿时长
6-12 weeks
期刊介绍: Multidisciplinary information with direct relevance to everyday practice Annales de Biologie Clinique, the official journal of the French Society of Clinical Biology (SFBC), supports biologists in areas including continuing education, laboratory accreditation and technique validation. With original articles, abstracts and accounts of everyday practice, the journal provides details of advances in knowledge, techniques and equipment, as well as a forum for discussion open to the entire community.
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