先天性弓形虫病:我们还应该关注筛查吗?

IF 2.9 Q2 PARASITOLOGY Food and Waterborne Parasitology Pub Date : 2022-06-01 DOI:10.1016/j.fawpar.2022.e00162

Eskild Petersen , Valeria Meroni , Daniel V. Vasconcelos-Santos , Laurent Mandelbrot , Francois Peyron

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引用次数: 5

摘要

自1975年以来，奥地利和法国已开始进行先天性弓形虫病的产前系统筛查，自1986年以来，新生儿先天性弓形虫病筛查已成为新英格兰新生儿筛查计划的一部分。在这篇叙述性综述中，我们回顾了导致奥地利和法国系统筛查项目的数据，重点介绍了欧盟在20世纪90年代和21世纪初资助的研究的主要发现。对产前或产后治疗效果的不同描述性研究进行了讨论。刚地弓形虫具有不同的遗传谱系，对人类具有不同的致病性。这意味着低致病性谱系地区的结果不能外推到高致病性谱系地区。鉴于弓形虫在有机牲畜生产中的流行率增加，本文讨论了肉类作为感染源的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Congenital toxoplasmosis: Should we still care about screening?

Prenatal systematic screening for congenital toxoplasmosis has been performed in Austria and France since 1975 and neonatal screening for congenital toxoplasmosis has been part of the New England Newborn screening program since 1986.

In this narrative review we review the data leading up to the systematic screening programs in Austria and France, highlighting the main finding of the European Union funded research in the 1990s and early 2000s. Different descriptive studies of the effect of pre- or postnatal treatment are discussed. Toxoplasma gondii has different genetic lineages with different pathogenicity in humans. This means that results in areas with a low pathogenic lineage cannot be extrapolated to an area with highly pathogenic lineages. The importance of meat as a source of infection is discussed in the light of an increased prevalence of T.gondii in organic livestock production .

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来源期刊

Food and Waterborne Parasitology Immunology and Microbiology-Parasitology

CiteScore

5.10

自引率

4.00%

发文量

审稿时长

13 weeks

期刊介绍： Food and Waterborne Parasitology publishes high quality papers containing original research findings, investigative reports, and scientific proceedings on parasites which are transmitted to humans via the consumption of food or water. The relevant parasites include protozoa, nematodes, cestodes and trematodes which are transmitted by food or water and capable of infecting humans. Pertinent food includes products of animal or plant origin which are domestic or wild, and consumed by humans. Animals and plants from both terrestrial and aquatic sources are included, as well as studies related to potable and other types of water which serve to harbor, perpetuate or disseminate food and waterborne parasites. Studies dealing with prevalence, transmission, epidemiology, risk assessment and mitigation, including control measures and test methodologies for parasites in food and water are of particular interest. Evidence of the emergence of such parasites and interactions among domestic animals, wildlife and humans are of interest. The impact of parasites on the health and welfare of humans is viewed as very important and within scope of the journal. Manuscripts with scientifically generated information on associations between food and waterborne parasitic diseases and lifestyle, culture and economies are also welcome. Studies involving animal experiments must meet the International Guiding Principles for Biomedical Research Involving Animals as issued by the Council for International Organizations of Medical Sciences.