VA-ECMO抢救红豆杉中毒心源性休克1例并文献复习。

Nikolaus Schreiber, Martin Manninger, Sascha Pätzold, Alexander C Reisinger, Stefan Hatzl, Gerald Hackl, Christoph Högenauer, Philipp Eller
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引用次数: 3

摘要

摄入欧洲紫杉(Taxus baccata)的叶子可导致致命的心律失常和急性心源性休克。这种心脏毒性来自于计程车生物碱阻断心脏电压门控钠和钙通道。由于没有解毒剂,及时开始静脉动脉体外膜氧合对于这些危重患者的康复至关重要。我们在此报告一位39岁的红豆杉中毒后中毒性心源性休克患者,经静脉动脉体外膜氧合成功抢救,神经系统完全恢复。该报告强调了中毒作为心脏骤停的可逆原因的作用,并为现有文献提供了进一步的证据,从而鼓励在红豆杉中毒和心源性休克患者中早期使用静脉体外膜氧合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Cardiogenic shock due to yew poisoning rescued by VA-ECMO: case report and literature review.

Ingestion of leaves of the European yew tree (Taxus baccata) can result in fatal cardiac arrhythmias and acute cardiogenic shock. This cardiotoxicity derives from taxine alkaloids that block cardiac voltage-gated sodium and calcium channels. Prompt initiation of venoarterial extracorporeal membrane oxygenation is essential to bridge these critically ill patients to recovery, as there is no antidote available. We here report a 39-year old patient with toxic cardiogenic shock after yew poisoning, who was successfully rescued by venoarterial extracorporeal membrane oxygenation and had a full neurological recovery. This report emphasizes the role of intoxications as reversible causes of cardiac arrest and adds further evidence to the body of existing literature thus encouraging the early use of venoarterial extracorporeal membrane oxygenation in patients with yew poisoning and cardiogenic shock.

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