-地中海贫血患者的FDG-PET/CT显示髓外造血功能。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Nuclear Medicine and Molecular Imaging Pub Date : 2022-12-01 Epub Date: 2022-09-20 DOI:10.1007/s13139-022-00773-3

Sara E Dahlsgaard-Wallenius, Karen Juul-Jensen, Anne Lerberg Nielsen, Malene Grubbe Hildebrandt

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引用次数: 0

摘要

地中海贫血是一种遗传性血液疾病，由血红蛋白β链合成减少或缺失引起，导致血红蛋白生成减少。症状取决于-地中海贫血的类型，从无症状到严重疾病不等。无效的红细胞生成导致一系列的事件负责骨髓扩张，贫血，溶血，脾肿大，铁吸收增加，有时髓外造血(EMH)。我们报告一个有趣的病例，在FDG-PET/CT上显示EMH，其中FDG-PET/CT也发现了β -地中海贫血患者严重感染的病灶。

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Extramedullary Hematopoiesis Visualized on FDG-PET/CT in a Patient with Beta-Thalassemia.

Beta-thalassemia is an inherited blood disorder caused by reduced or absent synthesis of the beta chains of hemoglobin, resulting in decreased hemoglobin production. Symptoms depend on the type of beta-thalassemia ranging from no symptoms to severe illness. Ineffective erythropoiesis leads to a sequence of events responsible for bone marrow expansion, anemia, hemolysis, splenomegaly, increased iron absorption, and sometimes extramedullary hematopoiesis (EMH). We report an interesting case with EMH visualized on FDG-PET/CT and where FDG-PET/CT has also found the focus of a severe infection in a patient with beta-thalassemia.

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来源期刊

Nuclear Medicine and Molecular Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

2.20

自引率

7.70%

发文量

期刊介绍： Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor. The Korean Society of Nuclear Medicine (KSNM) KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.