抗偏头痛药。

Pub Date : 2022-08-01 DOI:10.1358/dot.2022.58.8.3408815

Kate Bedrin, Jessica Ailani

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引用次数: 1

摘要

Atogepant是一种选择性口服小分子降钙素基因相关肽(CGRP)受体拮抗剂，已被批准用于偏头痛的预防性治疗。CGRP是一种参与血管舒张和脑血管调节的神经肽。CGRP是脑血管三叉神经系统中最有效的血管活性成分，在偏头痛中起关键作用。针对CGRP的药物被用于偏头痛的预防和流产治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Atogepant for migraine.

Atogepant is a selective oral, small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist that has been approved for preventive treatment of migraine. CGRP is a neuropeptide involved in vasodilation and cerebrovascular regulation. CGRP is the most potent vasoactive constituent of the cerebrovascular trigeminal neuronal system and has a key role in migraine. Medications targeting CGRP are being used as migraine preventive and abortive treatments.

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