R L WOLF, M MENDLOWITZ, L J SOFFER, J ROBOZ, S E GITLOW
{"title":"人体内促肾上腺皮质激素的代谢。","authors":"R L WOLF, M MENDLOWITZ, L J SOFFER, J ROBOZ, S E GITLOW","doi":"10.3181/00379727-119-30148","DOIUrl":null,"url":null,"abstract":"Summary Synthetic beta1-24 corticotropin has been labeled with I131 and intravenously administered to normal subjects. Analysis of the blood radioactivity following intravenous administration of beta1-24 corticotropin-I131 revealed that this substance has an apparent space of distribution of 43% of the body weight and a plasma half-life of 7 minutes.","PeriodicalId":20675,"journal":{"name":"Proceedings of the Society for Experimental Biology and Medicine","volume":" ","pages":"244-8"},"PeriodicalIF":0.0000,"publicationDate":"1965-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3181/00379727-119-30148","citationCount":"16","resultStr":"{\"title\":\"METABOLISM OF CORTICOTROPIN IN MAN.\",\"authors\":\"R L WOLF, M MENDLOWITZ, L J SOFFER, J ROBOZ, S E GITLOW\",\"doi\":\"10.3181/00379727-119-30148\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Summary Synthetic beta1-24 corticotropin has been labeled with I131 and intravenously administered to normal subjects. Analysis of the blood radioactivity following intravenous administration of beta1-24 corticotropin-I131 revealed that this substance has an apparent space of distribution of 43% of the body weight and a plasma half-life of 7 minutes.\",\"PeriodicalId\":20675,\"journal\":{\"name\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"volume\":\" \",\"pages\":\"244-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1965-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3181/00379727-119-30148\",\"citationCount\":\"16\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3181/00379727-119-30148\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Society for Experimental Biology and Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3181/00379727-119-30148","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Summary Synthetic beta1-24 corticotropin has been labeled with I131 and intravenously administered to normal subjects. Analysis of the blood radioactivity following intravenous administration of beta1-24 corticotropin-I131 revealed that this substance has an apparent space of distribution of 43% of the body weight and a plasma half-life of 7 minutes.
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