最初口服类固醇治疗后部分恢复的突发性感音神经性听力损失(SSNHL)的额外口服类固醇周期的疗效。

See-Ok Shin, Young-Seok Choi, Joo-Yeon Lee, Seung-Du Yoo
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引用次数: 6

摘要

结论:突发性感音神经性听力损失患者在初次口服类固醇治疗后部分恢复,再进行一次口服类固醇治疗无明显效果。目的:一个类固醇周期后听力的部分恢复可能是相对较短的用药时间的结果。我们评估了在这些患者中增加一个类固醇周期的疗效。对象和方法:我们按照严格的纳入标准,选择在一个类固醇治疗周期结束时听力增加大于10 dB,但听力水平仍低于30 dB的患者。他们被分为没有进一步治疗的对照组和接受额外周期类固醇治疗的研究组。我们比较了他们的听力结果、恢复率和平均听力改善持续时间。结果:单周期组和双周期组在听力结果、恢复率和平均听力改善时间方面均无显著差异。
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The efficacy of an additional cycle of oral steroids in partially recovered sudden sensorineural hearing loss (SSNHL) after initial oral steroid therapy.

Conclusion: There was no beneficial effect of an additional cycle of oral steroid therapy in partially recovered patients with sudden sensorineural hearing loss after initial oral steroid therapy.

Objectives: Partial recovery of hearing after one cycle of steroids might be the result of a relatively short duration of medication. We evaluated the efficacy of an additional cycle of steroids in those patients.

Subjects and methods: With strict inclusion criteria, we selected the patients with hearing gain more than 10 dB, but still worse than 30 dB with hearing level, at the end of one cycle of steroid therapy. They were divided into a control group with no further treatment and a study group treated with an additional cycle of steroids. We compared their hearing outcomes, recovery rates and the mean duration of hearing improvement.

Results: We could not find any significant difference in either hearing outcomes, recovery rates or the mean duration of hearing improvement between the one-cycled group and the two-cycled group.

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