【细胞衰老在慢性伤口愈合中的作用研究进展】。

Q3 Medicine Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns Pub Date : 2023-08-20 DOI:10.3760/cma.j.cn501225-20220928-00424

S Y H Fang, D W Liu

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引用次数: 0

摘要

慢性创伤由于其长期难治性特点和严重的不良预后，给患者、家属和社会带来了巨大的压力和困难。近年来，越来越多的证据表明，细胞衰老存在于慢性伤口中，并影响伤口愈合。本文综述了慢性伤口细胞衰老的特点，探讨了细胞衰老与慢性伤口愈合的关系，总结了目前一系列的抗衰老策略，为以细胞衰老为潜在靶点治疗慢性伤口提供了可能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Research advances on the role of cell senescence in chronic wound healing].

Chronic wounds bring huge pressure and difficulties to patients, their families, and society due to their long-term refractory characteristics and serious poor prognosis. Recently, more and more evidences have proven that cell senescence exists in chronic wounds and affects wound healing. This article reviews the characteristics of cell senescence in chronic wounds, discusses the relationship between cell senescence and chronic wound healing, and summarizes current series of anti-senescence strategies to bring out the possibility of treating chronic wounds with cell senescence as a potential target.

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来源期刊

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns Medicine-Medicine (all)

自引率

0.00%

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8511

期刊介绍： The Chinese Journal of Burns is the most authoritative one in academic circles of burn medicine in China. It adheres to the principle of combining theory with practice and integrating popularization with progress and reflects advancements in clinical and scientific research in the field of burn in China. The readers of the journal include burn and plastic clinicians, and researchers focusing on burn area. The burn refers to many correlative medicine including pathophysiology, pathology, immunology, microbiology, biochemistry, cell biology, molecular biology, and bioengineering, etc. Shock, infection, internal organ injury, electrolytes and acid-base, wound repair and reconstruction, rehabilitation, all of which are also the basic problems of surgery.