Donato Pezzulla, Alessia Re, Savino Cilla, Milena Ferro, Carmela Romano, Paolo Bonome, Rossella Di Franco, Paolo Muto, Giancarlo Mattiucci, Francesco Deodato, Gabriella Macchia
{"title":"脊柱不稳定新整形评分（SINS）作为常规放射治疗的预测工具：叙述性综述。","authors":"Donato Pezzulla, Alessia Re, Savino Cilla, Milena Ferro, Carmela Romano, Paolo Bonome, Rossella Di Franco, Paolo Muto, Giancarlo Mattiucci, Francesco Deodato, Gabriella Macchia","doi":"10.1080/07357907.2023.2269566","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>This narrative review seeks to identify the SINS score application in the radiation oncology field.</p><p><strong>Methods: </strong>This literature review was performed searching papers on MEDLINE published from January 2010 to August 2022.</p><p><strong>Results: </strong>In terms of vertebral painful lesions and RT symptomatic responses, the SINS score could be an interesting aid in order to choose the right therapeutic approach. Lesions with higher level of instability, and therefore higher SINS score, could did not find any significant benefit from radiation therapy which is more effective on the tumor-related pain component. For SINS as a predictor of adverse event after RT or its changes after RT, we obtained contrasting results.</p><p><strong>Conclusions: </strong>The reported few experiences showed ambiguous conclusions. Further prospective studies are needed.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Spine Instability Neoplastic Score (SINS) as a Predictive Tool in Conventional Radiotherapy: A Narrative Review.\",\"authors\":\"Donato Pezzulla, Alessia Re, Savino Cilla, Milena Ferro, Carmela Romano, Paolo Bonome, Rossella Di Franco, Paolo Muto, Giancarlo Mattiucci, Francesco Deodato, Gabriella Macchia\",\"doi\":\"10.1080/07357907.2023.2269566\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>This narrative review seeks to identify the SINS score application in the radiation oncology field.</p><p><strong>Methods: </strong>This literature review was performed searching papers on MEDLINE published from January 2010 to August 2022.</p><p><strong>Results: </strong>In terms of vertebral painful lesions and RT symptomatic responses, the SINS score could be an interesting aid in order to choose the right therapeutic approach. Lesions with higher level of instability, and therefore higher SINS score, could did not find any significant benefit from radiation therapy which is more effective on the tumor-related pain component. For SINS as a predictor of adverse event after RT or its changes after RT, we obtained contrasting results.</p><p><strong>Conclusions: </strong>The reported few experiences showed ambiguous conclusions. Further prospective studies are needed.</p>\",\"PeriodicalId\":9463,\"journal\":{\"name\":\"Cancer Investigation\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer Investigation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/07357907.2023.2269566\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/11/17 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Investigation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/07357907.2023.2269566","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/11/17 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
Spine Instability Neoplastic Score (SINS) as a Predictive Tool in Conventional Radiotherapy: A Narrative Review.
Aims: This narrative review seeks to identify the SINS score application in the radiation oncology field.
Methods: This literature review was performed searching papers on MEDLINE published from January 2010 to August 2022.
Results: In terms of vertebral painful lesions and RT symptomatic responses, the SINS score could be an interesting aid in order to choose the right therapeutic approach. Lesions with higher level of instability, and therefore higher SINS score, could did not find any significant benefit from radiation therapy which is more effective on the tumor-related pain component. For SINS as a predictor of adverse event after RT or its changes after RT, we obtained contrasting results.
Conclusions: The reported few experiences showed ambiguous conclusions. Further prospective studies are needed.
期刊介绍：
Cancer Investigation is one of the most highly regarded and recognized journals in the field of basic and clinical oncology. It is designed to give physicians a comprehensive resource on the current state of progress in the cancer field as well as a broad background of reliable information necessary for effective decision making. In addition to presenting original papers of fundamental significance, it also publishes reviews, essays, specialized presentations of controversies, considerations of new technologies and their applications to specific laboratory problems, discussions of public issues, miniseries on major topics, new and experimental drugs and therapies, and an innovative letters to the editor section. One of the unique features of the journal is its departmentalized editorial sections reporting on more than 30 subject categories covering the broad spectrum of specialized areas that together comprise the field of oncology. Edited by leading physicians and research scientists, these sections make Cancer Investigation the prime resource for clinicians seeking to make sense of the sometimes-overwhelming amount of information available throughout the field. In addition to its peer-reviewed clinical research, the journal also features translational studies that bridge the gap between the laboratory and the clinic.
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