噬菌体展示和人类疾病检测。

3区 生物学 Q2 Biochemistry, Genetics and Molecular Biology Progress in Molecular Biology and Translational Science Pub Date : 2023-01-01 Epub Date: 2023-06-17 DOI:10.1016/bs.pmbts.2023.03.022
Sonu Kumari, Krati Singh, Neha Singh, Suphiya Khan, Ajay Kumar
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引用次数: 0

摘要

噬菌体展示是一种重要而活跃的分子方法,在1985年被发掘的同时,它仍然对研究部门至关重要。这种做法有很多好处:生理学和基因组之间的联系,单一采集中显示的大量变异蛋白,以及可以实现的采集弹性。这表明操纵抗原附着的阶段多种多样;然而,展览馆的多样性和稳定性却给我们敲响了警钟。额外的改进,如非经典氨基酸的积累,导致可以通过收集识别的配体的扩展,将有助于扩大技术的可能用途和可能性。新冠肺炎的流行夺走了无数人的生命,尽管向患病者提供了指示性处方,但仍然没有观察到对污染的预防。噬菌体展示展示了对包括在发病机制中的蛋白质连接的深入理解。噬菌体展示知识正在发展成为一种有影响力、廉价、快速、有效的方法,为癌症的分子成像和分析培养新的介质。
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Phage display and human disease detection.

Phage display is a significant and active molecular method and has continued crucial for investigative sector meanwhile its unearthing in 1985. This practice has numerous benefits: the association among physiology and genome, the massive variety of variant proteins showed in sole collection and the elasticity of collection that can be achieved. It suggests a diversity of stages for manipulating antigen attachment; yet, variety and steadiness of exhibited library are an alarm. Additional improvements, like accumulation of non-canonical amino acids, resulting in extension of ligands that can be recognized through collection, will support in expansion of the probable uses and possibilities of technology. Epidemic of COVID-19 had taken countless lives, and while indicative prescriptions were provided to diseased individuals, still no prevention was observed for the contamination. Phage demonstration has presented an in-depth understanding into protein connections included in pathogenesis. Phage display knowledge is developing as an influential, inexpensive, quick, and effectual method to grow novel mediators for the molecular imaging and analysis of cancer.

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来源期刊
CiteScore
5.00
自引率
0.00%
发文量
110
审稿时长
4-8 weeks
期刊介绍: Progress in Molecular Biology and Translational Science (PMBTS) provides in-depth reviews on topics of exceptional scientific importance. If today you read an Article or Letter in Nature or a Research Article or Report in Science reporting findings of exceptional importance, you likely will find comprehensive coverage of that research area in a future PMBTS volume.
期刊最新文献
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