术前和围术期窄带成像内镜在喉肿瘤前和肿瘤病变诊断中的重要性。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-09-01 Epub Date: 2023-09-22 DOI:10.32725/jab.2023.015
Tomas Filipovsky, David Kalfert, Eva Lukavcova, Sarka Zavazalova, Jiri Hlozek, Daniel Kovar, Jaromir Astl, Richard Holy
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引用次数: 0

摘要

简介:窄带成像(NBI)是一种内窥镜成像方法,用于诊断在白光内窥镜中不可见的喉部粘膜病变,但却是典型的肿瘤前和肿瘤病变。本研究的目的:比较术前/围手术期白光内窥镜和NBI内窥镜与肿瘤前和肿瘤病变的组织病理学检查结果。方法:一项为期五年(2018年5月至2023年5月)的前瞻性研究,包括87名24-80岁的喉部病变患者。我们评估了术前/围手术期白光和NBI内窥镜检查,建立了有效的组织病理学诊断,并将其与喉部活检的最终组织病理学结果进行了比较。结果:关于最终组织学评分,术前和围手术期白光内窥镜和NBI内窥镜的发现评估与最终组织学之间存在统计学上显著的相关性(p<0.001)。两种方法在围手术期使用时都显示出更高的准确性。结论:NBI内窥镜检查是一种光学方法,可以提高对喉部病变的诊断,进行可控的围手术期活检,并细化手术范围。NBI内窥镜检查是诊断喉早期癌性病变的合适方法。术前/围手术期NBI内窥镜检查的使用使我们能够在组织病理学前工作诊断和最终组织病理学结果之间实现高度一致的相关性(p<0.001)。NBI方法证明了其在喉肿瘤前和肿瘤病变诊断中的应用。
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The importance of preoperative and perioperative Narrow Band Imaging endoscopy in the diagnosis of pre-tumor and tumor lesions of the larynx.

Introduction: Narrow band imaging (NBI) is an endoscopic imaging method intended for the diagnosis of mucosal lesions of the larynx that are not visible in white-light endoscopy, but are typical of pre-tumor and tumor lesions of the larynx.

The purpose of the study: To compare preoperative/perioperative white light endoscopy and NBI endoscopy with the results of histopathological examinations in pre-tumor and tumor lesions of the larynx.

Methods: A prospective study, over a period of five years (5/2018-5/2023), included 87 patients with laryngeal lesions aged 24-80 years. We evaluated preoperative/ perioperative white light and NBI endoscopy, established a working prehistological diagnosis, and compared this with the definitive histopathological results of laryngeal biopsies.

Results: In relation to the definitive histology score, a statistically significant correlation was found between the evaluation of the finding and the definitive histology for preoperative and perioperative white light endoscopy and NBI endoscopy (p < 0.001). Both methods showed higher precision when used perioperatively.

Conclusion: NBI endoscopy is an optical method that allows us to improve the diagnosis of laryngeal lesions, perform a controlled perioperative biopsy, and refine the surgical scope. The NBI endoscopy is a suitable method for the diagnosis of early cancerous lesions of the larynx. The use of preoperative/perioperative NBI endoscopy allowed us to achieve a high level of agreement correlation (p < 0.001) between the prehistological working diagnosis and the final histopathological result. The NBI method proves its application in the diagnosis of pre-tumor and tumor lesions of the larynx.

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ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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