内镜超声和内镜超声引导下组织采集在诊断肝脏局灶性病变中的作用。

Hussein Hassan Okasha, Hanane Delsa, Abdelmoneim Alsawaf, Ahmed Morad Hashim, Hani M Khattab, Dalia Abdelfatah, Abeer Abdellatef, Amr Albitar
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引用次数: 0

摘要

背景:内镜超声检查(EUS)已成为胃肠病诊断和治疗程序中的一种既定方法;然而,它最近在肝病学中的作用越来越大。目的:评估EUS特征、应变弹性成像(SE)和EUS组织采集在诊断肝局灶性病变(HFL)中的作用,这些病变可能会影响进一步的治疗。方法:这项横断面研究纳入了215名胰腺、胆道或胃肠道恶性肿瘤患者进行EUS检查。在43名患者(20%)中发现了HFL,并对这些病变进行了EUS引导的组织采集。结果:超声心动图特征对HFL的诊断敏感性高(100%),但特异性低(57%);总体准确率为94%。实时弹性成像在诊断HFL方面也非常敏感(97%),但特异性较低(67%);但总体准确率为92%。EUS组织采集具有极高的敏感性(100%)和特异性(100%),总体诊断准确率为100%。结论:EUS引导下的组织采集对HFL的诊断非常准确。EUS特征和实时SE准确预测了良性和恶性HFL的组织学诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Role of endoscopic ultrasound and endoscopic ultrasound-guided tissue acquisition in diagnosing hepatic focal lesions.

Background: Endoscopic ultrasonography (EUS) has become an established method in diagnostic and therapeutic procedures in gastroenterology; however, it has recently gained a growing role in hepatology.

Aim: To evaluate the role of EUS features, strain elastography (SE), and EUS-tissue acquisition in diagnosing hepatic focal lesions (HFLs) that could affect further management.

Methods: This cross-sectional study included 215 patients with pancreatic, biliary, or gastrointestinal malignancies referred for EUS examination. HFLs were identified in 43 patients (20%), and EUS-guided tissue acquisition was performed from these lesions.

Results: EUS features were highly sensitive (100%) but much less specific (57%) in diagnosing HFLs; the overall accuracy was 94%. Real-time elastography was also very sensitive (97%) but less specific (67%) in diagnosing HFLs; however, the overall accuracy was 92%. EUS tissue acquisition was extremely sensitive (100%) and specific (100%), with a 100% overall diagnostic accuracy.

Conclusion: The diagnostic utility of EUS-guided tissue acquisition was extremely accurate in diagnosing HFLs. EUS characteristics and real-time SE accurately predicted the histological diagnosis of both benign and malignant HFLs.

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