一名17岁女孩因伊曲康唑引起的嗜酸性粒细胞增多症和系统症状综合征药物皮疹。

IF 1.1 4区医学 Q4 ALLERGY Pediatric Allergy Immunology and Pulmonology Pub Date : 2023-12-01 Epub Date: 2023-09-20 DOI:10.1089/ped.2023.0066

Helena Pires Pereira, Iolanda Alen Coutinho, Isabel Carrapatoso, Ana Todo-Bom

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引用次数: 0

摘要

伴有嗜酸性粒细胞增多和全身症状的皮疹（DRESS）综合征是一种严重的药物引起的过敏反应。我们报告了一例由伊曲康唑引起的17岁女性DRESS综合征，经贴片试验证实，需要同时使用皮质类固醇和环孢菌素治疗。我们的病例强调了临床怀疑该综合征在儿童年龄的重要性，以及一种抗真菌药物被确定为罪魁祸首的新颖性。

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Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Caused by Itraconazole in a 17-Year-Old Girl.

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a severe adverse drug-induced hypersensitivity reaction. We report a case of DRESS syndrome in a 17-year-old female caused by itraconazole, confirmed by patch testing, that required treatment with both corticotherapy and cyclosporine. Our case highlights the importance of clinical suspicion of this syndrome in pediatric age and the novelty of an antifungal drug being identified as the culprit.

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来源期刊

Pediatric Allergy Immunology and Pulmonology ALLERGY-IMMUNOLOGY

CiteScore

2.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Pediatric Allergy, Immunology, and Pulmonology is a peer-reviewed journal designed to promote understanding and advance the treatment of respiratory, allergic, and immunologic diseases in children. The Journal delivers original translational, clinical, and epidemiologic research on the most common chronic illnesses of children—asthma and allergies—as well as many less common and rare diseases. It emphasizes the developmental implications of the morphological, physiological, pharmacological, and sociological components of these problems, as well as the impact of disease processes on families. Pediatric Allergy, Immunology, and Pulmonology coverage includes: -Functional and genetic immune deficiencies- Interstitial lung diseases- Both common and rare respiratory, allergic, and immunologic diseases- Patient care- Patient education research- Public health policy- International health studies