2012年至2021年肝细胞癌经动脉化疗栓塞的研究趋势:文献计量学分析。

Na Zhang, Xiao-Feng He, Xiang-Ke Niu
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引用次数: 0

摘要

背景:肝细胞癌(HCC)是全球第五大癌症,也是癌症相关死亡的第二大原因。经导管动脉化疗栓塞(TACE)是一种将旨在减缓或阻止肿瘤发展的药物注射到HCC组织的动脉中的治疗方法。综合分析所有关于肝癌TACE的文章,可以让我们大致了解该领域的进展,并为未来的研究提供指导。目的:分析和可视化TACE治疗HCC的科学结果和研究趋势。方法:使用“Web of Science”数据库来识别2012年至2021年关于TACE治疗肝癌的文章。VOSviewer和CiteSpace用于分析出版物趋势、国家/机构/作者之间的合作,以及关键词、关键词突发和参考文献的共同出现。结果:共检索到5728篇关于肝细胞癌TACE的原始文章。关于出版物数量,年度出版物总数总体呈增长趋势。中国的文章数量最高,而美国的赫希指数和引用次数最高。中国的中山大学是最多产的学府。最活跃的作家是来自韩国的朴。《血管与介入放射学杂志》(234篇文章)是产量最高的期刊。肝细胞癌TACE的国际合作趋势日益明显。共引参考文献的集群网络表明,实践指南和靶向治疗是该领域的一个重要主题。此外,基于关键词共现的聚类分析将研究主题“TACE治疗的预测”确定为热点,倾向得分匹配可用于帮助研究人员在未来进行创新研究。结论:文献计量学分析结果为肝细胞癌TACE治疗提供了最新趋势和热点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Mapping research trends of transarterial chemoembolization for hepatocellular carcinoma from 2012 to 2021: A bibliometric analysis.

Background: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the second leading cause of cancer-related deaths. Transcatheter arterial chemoembolization (TACE) is a therapy where drugs aimed to slow or halt tumor development are injected into the artery supplying for HCC tissues. A comprehensive analysis of all the articles on TACE for HCC can give us a general understanding of the progress in this field and provide guidance for future research.

Aim: To analyze and visualize scientific results and research trends in TACE treatment for HCC.

Methods: The "Web of Science" database was used to identify articles regarding TACE for the treatment of HCC from 2012 to 2021. VOSviewer and CiteSpace were used to analyze the publications trends, collaboration between countries/insti-tutions/authors, and the co-occurrence of keywords, keyword bursts, and references.

Results: A total of 5728 original articles on TACE for HCC were retrieved. Regarding the volume of publications, the total number of yearly publications showed a generally increasing trend. China had the highest number of articles, while the United States achieved the highest Hirsch index and highest number of citations. The Sun Yat-sen University in China was most prolific institution. The most active author was Park, J.W from South Korea. The Journal of Vascular and Interventional Radiology (234 articles) was the most productive journal. There is a growing trend toward international collaboration in TACE for HCC. Cluster networks of co-cited references suggested that practice guidelines and targeted therapies are an essential theme in this field. In addition, cluster analysis based on keyword co-occurrence identified the research topic "prediction of TACE treatment" as a hotspot, and propensity score matching can be used to help investigators conduct innovative studies in the future.

Conclusion: The results of our bibliometric analysis provide the latest trends and hot topics in TACE therapy for HCC.

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