欧洲核医学中使用的新型放射性核素:我们的立场和方向?

IF 4.4 Q1 CHEMISTRY, INORGANIC & NUCLEAR EJNMMI Radiopharmacy and Chemistry Pub Date : 2023-10-12 DOI:10.1186/s41181-023-00211-5
Maija Radzina, Laura Saule, Edgars Mamis, Ulli Koester, Thomas Elias Cocolios, Elina Pajuste, Marika Kalnina, Kristaps Palskis, Zoe Sawitzki, Zeynep Talip, Mikael Jensen, Charlotte Duchemin, Kirsten Leufgen, Thierry Stora
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引用次数: 0

摘要

背景:为了支持欧洲各地正在进行的研究,以促进获得新型放射性核素,成立了PRISMAP联盟(欧洲医用放射性核素计划),为医学和转化研究提供最广泛的非常规放射性核素目录。本文旨在向读者介绍欧洲新型放射性核素的现状。正文:通过PRISMAP联盟和欧洲的用户社区、专业协会和临床前/临床最终用户分发了一份联盟问卷,并确定了核医学临床最终用户的现状。共有40家临床前/临床用户机构参与了调查。临床最终用户目前在研究中使用以下放射性核素:177Lu、68Ga、111In、90Y、其他α发射体、225Ac、64Cu和铽同位素。用户在未来2-5年内感兴趣的放射性核素是64Cu、铽放射性核素“家族”和α发射器,如225Ac。结论:由于PRISMAP联盟分发的问卷,确定了核医学临床最终用户的现状和需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Novel radionuclides for use in Nuclear Medicine in Europe: where do we stand and where do we go?

Background

In order to support the ongoing research across Europe to facilitate access to novel radionuclides, the PRISMAP consortium (European medical radionuclides programme) was established to offer the broadest catalog of non-conventional radionuclides for medical and translational research. The aim of this article is to introduce readers with current status of novel radionuclides in Europe.

Main body

A consortium questionnaire was disseminated through the PRISMAP consortium and user community, professional associations and preclinical/clinical end users in Europe and the current status of clinical end-users in nuclear medicine were identified. A total of 40 preclinical/clinical users institutions took part in the survey. Clinical end users currently use the following radionuclides in their studies: 177Lu, 68 Ga, 111In, 90Y, other alpha emitters, 225Ac, 64Cu and Terbium isotopes. Radionuclides that would be of interest for users within the next 2–5 years are 64Cu, Terbium radionuclide “family” and alpha emitters, such as 225Ac.

Conclusions

Thanks to a questionnaire distributed by the PRISMAP consortium, the current status and needs of clinical end-users in nuclear medicine were identified.

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CiteScore
7.20
自引率
8.70%
发文量
30
审稿时长
5 weeks
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