化妆品治疗减轻婴儿、儿童和成人轻度至中度特应性皮炎的疗效:一项初步研究

IF 3.4 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Cosmetics Pub Date : 2023-08-21 DOI:10.3390/cosmetics10040117
Vincenzo Nobile, Valentina Zanoletti, Marta Pisati, Enza Cestone
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引用次数: 0

摘要

特应性皮炎(AD)是一种慢性炎症性和瘙痒性皮肤病,其发病率在全球范围内呈逐渐上升趋势。在这项临床研究中,我们研究了由清洁剂、身体和面霜组成的美容治疗对患有轻度至中度AD的受试者(婴儿、儿童和成人)的影响。通过SCORing特应性皮炎(SCORAD)指数、主观评价、皮肤红斑指数和经皮失水(TEWL)测量,研究了产品对AD临床症状的影响。这些产品在所有组中都被证明能有效改善SCORAD的AD评分,并且在成年人群中有红斑指数和TEWL下降的趋势。受试者还报告了瘙痒感、皮肤发红和皮肤干燥评分的改善。这项研究的结果表明,经过28天的治疗,受试产品在降低总体AD严重程度方面具有疗效。总的来说,第一个结果发生在治疗的14天内。
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Efficacy of a Cosmetic Treatment in Decreasing the Mild-to-Moderate Atopic Dermatitis in Babies, Children, and Adults: A Pilot Study
Atopic dermatitis (AD) is a chronic inflammatory and pruritic skin disease with a worldwide progressive increase in its incidence. In this clinical study, we studied the effect of a cosmetic treatment composed of a cleanser, and a body and face cream, on subjects (babies, children, and adults) suffering from mild-to-moderate AD. The product effect on AD clinical signs was investigated by SCORing Atopic Dermatitis (SCORAD) index, subjective evaluation, skin erythema index, and transepidermal water loss (TEWL) measurements. The products were shown to be effective in improving the AD scoring by SCORAD in all the groups, and a trend towards the decrease of the erythema index and the TEWL in the adult population. An improvement in itching sensation, skin redness, and skin dryness scoring was also reported by the subjects. Results from this study demonstrate the efficacy of the tested products in decreasing the overall AD severity through 28 days of treatment. Overall, the first results occurred within 14 days of treatment.
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来源期刊
Cosmetics
Cosmetics Medicine-Surgery
CiteScore
5.20
自引率
12.10%
发文量
108
审稿时长
8 weeks
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