胰腺和肾脏同时移植后严重感染并伴有腿部皮肤坏死。病例报告。

Q4 Medicine Transplantation Reports Pub Date : 2020-09-01 DOI:10.1016/j.tpr.2020.100049
Grzegorz Witkowski , Marta Matejak-Górska , Marek Durlik
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引用次数: 1

摘要

免疫抑制潜力的增加降低了移植器官排斥反应的发生率,但也增加了患者对机会性感染和癌症的易感性。患者男,37岁,因右腿水肿伴感染征象而入住普通及移植外科。药物治疗效果不佳,行手术切除。术后开始负压创面治疗,并行裂皮植皮术。几周后患者出院,无活动性感染迹象,伤口愈合良好。免疫功能低下患者的皮肤感染应迅速接受积极的手术清创和广谱抗生素治疗,因为这类人群发生危及生命的并发症的风险很高。
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Severe infection with skin necrosis of the leg after simultaneous pancreas and kidney transplantation. Case report.

The increase potential of immunosupression have reduced the incidence of transplanted organs rejection but also increased patients susceptibility to opportunistic infections and cancer.

37-year-old male patient was admitted to the Department of General and Transplantation Surgery due to edema of the right leg with signs of infection. Pharmacological treatment was not effective enough and surgical necrosectomy was performed. After that negative pressure wound therapy was started and split-thick skin grafting was done. After few weeks patient was discharged without any signs of active infection, with good healing wound.

Cutaneous infection in immunocompromised patients should be treated quickly with aggressive surgical debridement and wide-spectrum antibiotics because of the high risk of life-threating complications in this population.

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来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
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