嗅探棒气味阈值和识别的自我测试——恢复“纸上气味曲线”方法

IF 1 4区 医学 Q4 Neuroscience Chemosensory Perception Pub Date : 2019-04-04 DOI:10.1007/s12078-019-09263-x
Gerold Besser, David Tianxiang Liu, Bertold Renner, Christian A. Mueller
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引用次数: 10

摘要

嗅觉测试有助于诊断嗅觉功能障碍。嗅嗅棒气味测试套件广泛用于研究,可以重复使用,阈值(T),歧视(D)和识别(I)的总分数允许与规范数据进行比较。测试可能很耗时,而且气味笔必须由考官出示。本研究的目的是探讨自我给药策略来检测T和d。纳入50名健康受试者,其中女性30名,男性20名,平均年龄27.3岁±8.1岁,年龄范围18-58岁。T由检查者(T-as)以反阶梯方式进行测试,并采用随机呈现的浓度(T-rand)和上升极限法(T-aml)进行自测。D测试在辅助(D-as)和自我管理(D-s)下进行。对于自测,考生被要求执行“纸上气味曲线”法。TDI平均值35.9±3.0,范围26.5 ~ 42.8。T-as评分显著低于T-aml (p < 0.001)和T-rand (p < 0.05)。T-aml明显快于T-rand和T-as模式(p < 0.001);配对t检验显示,d -a和D-s在得分和所需时间方面无显著差异(p >?0.05),平均差异很小(0.3)。本研究结果表明,“纸上气味曲线”方法适用于D检验,但对T检验有一定的限制。在适当的指导下,使用嗅探棒进行自我嗅觉测试可以很容易地进行,并且可以改善人员和(有限的)时间限制环境中的患者护理。
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Self-Administered Testing of Odor Threshold and Discrimination Using Sniffin’ Sticks—Reviving the “Odor-Curves-On-Paper” Method

Olfactory testing helps in diagnosing olfactory dysfunction (OD). The Sniffin’ Sticks odor test kit is widely used for research and can be reused and summed scores of threshold (T), discrimination (D), and identification (I) allow comparison to normative data. Testing can be time consuming and odor pens have to be presented by an examiner. The aim of this study was to investigate for a self-administration strategy for testing T and D.

Fifty healthy subjects (30 female, 20 male, mean age 27.3?years?±?8.1, range 18–58) were included. T was tested by an examiner (T-as) in a reversed staircase manner and self-tested with randomly presented concentrations (T-rand) and ascending methods of limits (T-aml). D testing was performed with assistance (D-as) and self-administered (D-s). For self-testing, examinees were instructed to perform the “odor-curves-on-paper” method.

Mean TDI was 35.9?±?3.0, range 26.5–42.8. T-as scores were significantly lower than T-aml (p?<?0.001) and T-rand (p?<?0.05). T-aml was significantly faster than T-rand and T-as modalities (p?<?0.001); Paired t test revealed no significant difference of D-as and D-s, in terms of scores and time needed (p?>?0.05) and the mean difference was small (0.3).

The results of this study demonstrate the “odor-curves-on-paper” method is applicable for D and with restrictions for T testing.

Self-administration of olfactory testing using Sniffin’ Sticks can, with appropriate instructions, easily be performed and may improve patient care in personnel and (with limitations) time-restricted settings.

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来源期刊
Chemosensory Perception
Chemosensory Perception 农林科学-神经科学
CiteScore
2.50
自引率
0.00%
发文量
8
审稿时长
>36 weeks
期刊介绍: Coverage in Chemosensory Perception includes animal work with implications for human phenomena and explores the following areas: Identification of chemicals producing sensory response; Identification of sensory response associated with chemicals; Human in vivo response to chemical stimuli; Human in vitro response to chemical stimuli; Neuroimaging of chemosensory function; Neurological processing of chemoreception; Chemoreception mechanisms; Psychophysics of chemoperception; Trigeminal function; Multisensory perception; Contextual effect on chemoperception; Behavioral response to chemical stimuli; Physiological factors affecting and contributing to chemoperception; Flavor and hedonics; Memory and chemoperception.
期刊最新文献
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