{"title":"甲氨蝶呤在绝经后低恶性指数单纯性卵巢囊肿中的应用","authors":"Shereef Elshwaikh","doi":"10.33552/wjgwh.2021.04.000599","DOIUrl":null,"url":null,"abstract":"Objective: To evaluate Intracystic injection of methotrexate in postmenopausal female suffering from simple ovarian cyst with low malignancy index. Methods: Clinical randomized controlled study, two group of post-menopausal females each group had 25 patients with ovarian cyst with low malignancy index (less than 25), group I : underwent ultrasound guided aspiration of the cyst followed by methotrexate injection Group II: had no interference. Both group will be followed up for 6 months . Results: Epidemiological data and the characteristics of the cyst at the beginning of the study showed insignificant relationship between two groups. In group I (study group) the time of the procedure was 12.15±1.035 min., with no complications. After follow up of the cases for 6 month it shows significant difference as regard recurrence / persistence of the cyst ( I case recurred in group1 ,and 15 case persist in group 2) with P value 0.000022 .While there was insignificant relationship as regard new symptoms , presence of complications and need for surgery . Conclusion: This technique is considered a promising technique for its management, but it couldn’t be recommended by our study as this process is invasive and it shows only single advantage over expectant management.","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Intracystic Injection of Methotrexate in Postmenopausal Female Suffering from Simple Ovarian Cyst with Low Malignancy Index\",\"authors\":\"Shereef Elshwaikh\",\"doi\":\"10.33552/wjgwh.2021.04.000599\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To evaluate Intracystic injection of methotrexate in postmenopausal female suffering from simple ovarian cyst with low malignancy index. Methods: Clinical randomized controlled study, two group of post-menopausal females each group had 25 patients with ovarian cyst with low malignancy index (less than 25), group I : underwent ultrasound guided aspiration of the cyst followed by methotrexate injection Group II: had no interference. Both group will be followed up for 6 months . Results: Epidemiological data and the characteristics of the cyst at the beginning of the study showed insignificant relationship between two groups. In group I (study group) the time of the procedure was 12.15±1.035 min., with no complications. After follow up of the cases for 6 month it shows significant difference as regard recurrence / persistence of the cyst ( I case recurred in group1 ,and 15 case persist in group 2) with P value 0.000022 .While there was insignificant relationship as regard new symptoms , presence of complications and need for surgery . Conclusion: This technique is considered a promising technique for its management, but it couldn’t be recommended by our study as this process is invasive and it shows only single advantage over expectant management.\",\"PeriodicalId\":87379,\"journal\":{\"name\":\"World journal of gynecology & womens health\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World journal of gynecology & womens health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33552/wjgwh.2021.04.000599\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World journal of gynecology & womens health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33552/wjgwh.2021.04.000599","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Intracystic Injection of Methotrexate in Postmenopausal Female Suffering from Simple Ovarian Cyst with Low Malignancy Index
Objective: To evaluate Intracystic injection of methotrexate in postmenopausal female suffering from simple ovarian cyst with low malignancy index. Methods: Clinical randomized controlled study, two group of post-menopausal females each group had 25 patients with ovarian cyst with low malignancy index (less than 25), group I : underwent ultrasound guided aspiration of the cyst followed by methotrexate injection Group II: had no interference. Both group will be followed up for 6 months . Results: Epidemiological data and the characteristics of the cyst at the beginning of the study showed insignificant relationship between two groups. In group I (study group) the time of the procedure was 12.15±1.035 min., with no complications. After follow up of the cases for 6 month it shows significant difference as regard recurrence / persistence of the cyst ( I case recurred in group1 ,and 15 case persist in group 2) with P value 0.000022 .While there was insignificant relationship as regard new symptoms , presence of complications and need for surgery . Conclusion: This technique is considered a promising technique for its management, but it couldn’t be recommended by our study as this process is invasive and it shows only single advantage over expectant management.