影响高血压患者生存时间的因素分析

Abtsega Samuel Ayalew, Markos Abiso Erango, K. Gergiso
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引用次数: 3

摘要

高血压是一种主要的长期健康状况,也是心血管疾病和死亡的主要可变风险因素。本研究的目的是检查影响随访中高血压患者生存时间的主要因素。我们考虑了2013年1月至2019年1月在埃塞俄比亚Yekatit-12医院接受随访的430名高血压患者的随机样本。采用指数、威布尔、对数正态和对数逻辑四种参数加速失效时间分布来分析患者的生存概率。Kaplan-Meiereestimation方法和对数秩检验用于比较不同协变量患者的生存经验。威布尔模型被选择为最适合数据集。结果表明,患者的基线年龄、居住地、高血压家族史、卡塔叶摄入量、患者血胆固醇水平、高血压疾病分期、坚持治疗及相关疾病与高血压患者的生存时间显著相关。但性别、吸烟、饮酒、糖尿病和空腹血糖等因素并不是显著相关因素。社会和所有利益相关者都应该意识到这些因素的后果,这些因素会影响高血压患者的生存时间。
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Survival Analysis of Factor Affects Survival Time of Hypertension Patients
Hypertension is a major long-term health condition and a leading modifiable risk factor for cardiovascular disease and death. The aim of this study was to examine major factors that affect survival time of hypertension patients under follow-up. We considered a total of 430 random samples of hypertension patients who had been under follow up at Yekatit-12 Hospital in Ethiopia from January 2013 to January 2019. Four parametric accelerated failure time distributions: Exponential, Weibull, Lognormal and loglogistic are used to analyse survival probabilities of the patients. The Kaplan-Meierestimation method and log-rank tests were used to compare the survival experience of patients with respect to different covariates. The Weibull model is selected to best fit to the data sets. The results indicate that the baseline age of the patient, place of residence, family history of hypertension, khat intake, blood cholesterol level of the patient, hypertension disease stage, adherence to the treatment and related disease were significantly associated with survival time of hypertension patients. But factor like gender, tobacco use, alcohol use, diabetes mellitus status and fasting blood sugar were not significantly associated factors. Society and all stakeholders should be aware of the consequences of these factors which can influence the survival time of hypertension patients.
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