重症监护室多发性鲍曼不动杆菌感染的相关因素。多中心研究

Q4 Immunology and Microbiology Boletin De Malariologia Y Salud Ambiental Pub Date : 2023-01-30 DOI:10.52808/bmsa.8e7.631.004
G. Vásquez-Tirado
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引用次数: 0

摘要

分析在秘鲁北部特鲁希略市重症监护室(ICU)接受治疗的多重耐药鲍曼不动杆菌(MDR-Ab)感染的相关因素。病例对照研究回顾了秘鲁北部特鲁希略市三家主要医院入住重症监护室的60名患者的医疗记录,根据是否存在耐多药鲍曼不动杆菌感染进行了划分(每组30名患者)。计算主要假定相关因素的OR,然后进行多变量分析。有和无MDR-Ab患者的平均年龄分别为60.3和46.3岁,75岁以上与MDR-Ab显著相关,90%的Ab-MDR患者出现ICU延长。耐多药耐药性(OR:13.5,p<0.001),86.7%的耐多药感染患者以低蛋白血症为主(OR:4.33,p=0.041),83.3%的耐多药物耐药性抗体患者暴露于中心静脉导管(CVC)(OR:3.82;p=0.049),同样,所有患者都曾接受过抗生素治疗。多因素分析显示,ICU住院时间延长(p=0.035)和CVC使用时间延长(p=0.008)与MDR-Ab感染独立相关。长期入住重症监护室和使用CVC是相关因素
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Factores asociados a infección por Acinetobacter baumannii multidrogorresistente en unidad de cuidados intensivos. Estudio multicéntrico
To analyze the factors associated with multidrug-resistant Acinetobacter baumannii (MDR-Ab) infection, treated at the intensive care unit (ICU) in the city of Trujillo, northern Peru. Case-control study in which 60 medical records of patients admitted to the ICU from three main hospitals in the city of Trujillo in northern Peru were reviewed, divided according to the presence or absence of multidrug-resistant A. baumannii infection (30 patients per group). The OR of the main postulated associated factors was calculated, then a multivariate analysis was performed. The average age was 60.3 and 46.3 years in patients with and without MDR-Ab respectively, being over 75 years old was significantly associated with MDR-Ab, prolonged ICU stay occurred in 90% of patients with Ab-MDR. MDR (OR: 13.5, p<0.001), hypoalbuminemia predominated in 86.7% of patients with MDR infection (OR: 4.33, p=0.041), 83.3% of patients with MDR-Ab were exposed to a central venous catheter (CVC) (OR:3.82; p=0.049), likewise, all patients had previous antibiotic therapy. Multivariate analysis showed that prolonged ICU stay (p=0.035) and CVC use (p=0.008) were independently associated with MDR-Ab infection. Prolonged stay in the ICU and the use of CVC are factors associated
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来源期刊
Boletin De Malariologia Y Salud Ambiental
Boletin De Malariologia Y Salud Ambiental INFECTIOUS DISEASES-PARASITOLOGY
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