胶原蛋白:一种有前景的生物医学应用分子

IF 0.5 Q4 ENGINEERING, BIOMEDICAL Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-05-31 DOI:10.4028/p-v5a3hl
Angie Tatiana Toro Martinez, R. Buitrago‐Sierra, Alvaro Guzmán Aponte
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引用次数: 0

摘要

胶原蛋白在生物医学领域有着广泛的应用,主要用于构建细胞生长和分化的结构(细胞支架)。这种生物分子也用于化妆品,因为它是某些化妆品的基本成分,也是治疗伤口和烧伤的绷带的药物成分。然而,胶原蛋白的使用一直受到其提取来源(通常是动物)的伦理和道德影响的限制。因此,应该寻找更环保的替代来源来获取胶原蛋白。从捕鱼业废料(如鱼鳞、骨头和鱼皮)中提取胶原蛋白已被认为是获得这种生物材料的一种有利的替代方法,由于其与人体结构(器官和组织)的生物相容性,也显示出有希望的结果。该分子的特性和其他可获得该分子的来源有待进一步研究。
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Collagen: A Promising Molecule in Biomedical Applications
Collagen has been widely used in biomedical applications, mainly to develop structures (cell scaffolds) that allow cell growth and differentiation processes. This biomolecule is also used in cosmetics because it is an essential ingredient of certain makeup and in pharmaceutics for bandages to treat wounds and burns. However, the use of collagen has been limited by the ethical and moral implications of the (typically animal) sources from which it is extracted. Therefore, alternative, more environmentally friendly sources should be found to obtain collagen. Extracting collagen from fishing industry waste (such as scales, bones, and fish skin) has been presented as an advantageous alternative to obtain this biomaterial, which has also shown promising results due to its biocompatibility with human structures (organs and tissues). The characteristics of this molecule and other sources from which it can be obtained should be further studied.
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CiteScore
1.40
自引率
14.30%
发文量
73
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