糖皮质激素脉冲治疗炎性眼窝疾病的疗效:1例报告

Ioana-Codruța Lebădă, M. Stanciu
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摘要

眼眶假瘤是一种眼眶良性炎性疾病,病因不明,其临床表现与Basedow病即Graves眼病的眼部病理相似,这两种眼病代表了眼眶最常见的两种情况。影像学方法和实验室分析可以通过眼眶MRI图像确定眼眶假性肿瘤的诊断,特别是通过TSH受体抗体(TRAb)的剂量,在baseddow病伴眼损伤时具有更高的价值。在这两种情况下,治疗都是通过高剂量的口服或静脉注射皮质疗法作为第一个治疗路线,进展良好,这在我们的患者中也可以观察到,该患者根据MRI图像诊断为眼眶假性肿瘤,伴有甲状腺功能障碍,TRAb阴性,其中使用索美地醇脉冲治疗确定了眼部症状和体征的改善。
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The Efficiency of Pulse Therapy with Glucocorticoids in Inflammatory Orbital Disorders: Case Report
Abstract Orbital pseudotumor represents a benign inflammatory disorder of the orbit, with unspecified etiology, whose clinical presentation can mimic the ocular pathology of Basedow disease, namely Graves’ ophthalmopathy, the two of them representing two of the most common orbital conditions. Imagistic methods and laboratory analyses can establish the diagnosis through orbital MRI images specific for the orbital pseudotumor, especially by dosage of the TSH receptor antibodies (TRAb) which will have increased values in Basedow disease with ocular damage. In both situations, the treatment is represented as a first therapeutic line by administration of corticotherapy in high dosage orally or intravenously, with favorably evolution, which is also observable in the case of our patient who was diagnosed with orbital pseudotumor based on MRI images, with associated thyroid dysfunction with negative TRAb, in which the pulse therapy with Solumedrol has determined the improvement of ocular symptoms and signs.
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