自闭症谱系障碍患者的健康状况

Vladimir Trajkovski
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引用次数: 9

摘要

简介:自闭症谱系障碍(ASD)是一种行为定义的综合征,其病因和病理生理学尚不清楚。如果孩子被诊断为自闭症,父母就会面临特殊的行为挑战。使自闭症谱系障碍更加困难的是,在这一人群中经常出现的许多其他医疗健康问题。本文的目的是总结自闭症通常相关的身体和精神健康状况的最新认识。方法:对相关文献、网络来源和已发表文献、个人经历和作者观察进行分析。最近的研究发现:自闭症是一种全身紊乱。常与以下疾病合并症:癫痫、胃肠疾病、神经炎症和免疫疾病、哮喘、湿疹、睡眠障碍、饮食和喂养障碍、食物过敏、注意力缺陷和多动障碍(ADHD)、头痛、焦虑症、双相情感障碍、抑郁症、精神分裂症、强迫症、脆性X综合征、智力残疾、非语言学习障碍、运动笨拙、图雷特综合症、感觉问题、结节性硬化症、氧化应激、获得性线粒体功能障碍和代谢异常。这里列出的许多问题可能相互重叠。结论:提高对ASD的潜在病理及相关疾病的认识,并在多个治疗场所建立共同的目标,可以改善自闭症儿童的一致和协调的医疗保健。有必要制定改进的战略,向这一庞大人口提供有效的健康教育和保健。提高这些人过相对独立生活的能力具有巨大的经济影响。
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HEALTH CONDITION IN PERSONS WITH AUTISM SPECTRUM DISORDERS
Introduction: Autism Spectrum Disorders (ASD) are behaviourally defined syndromes where the etiology and pathophysiology are not very well understood. If the child has been diagnosed with autism, parents already face special behavioural challenges. What makes ASD even more difficult, are the many other medical health issues that often arise in this population.The purpose of this article is to summarise the latest understanding of autism’s commonly associated physical and mental health conditions.Methods: An analysis of relevant literature, sources from the internet and published literature, personal experience and observations of the author.Recent findings: Autism is a disorder of the whole body. It is often in co-morbidity with: epilepsy, gastrointestinal disorders, neuro-inflammation and immunological disorders, asthma, eczema, sleep disturbances, eating and feeding disorders, food allergies, attention deficit and hyperactivity disorder (ADHD), headaches, anxiety disorders, bipolar disorder, depression, schizophrenia, obsessive-compulsive disorder, Fragile X syndrome, intellectual disability, nonverbal learning disorder, motor clumsiness, Tourette syndrome, sensory problems, tuberous sclerosis, oxidative stress, acquired mitochondrial dysfunction and metabolic abnormalities. Many of the issues outlined here can overlap each other.Conclusions:Improved understanding of the underlying pathology of ASD and associated conditions, and the development of a common purpose across multiple treating sites, can improve the consistent and coordinated healthcare of children with autism. There is need for the development of improved strategies for delivering effective health education and healthcare to this large population. Improving the ability of these persons to lead relatively independent lives has a great economic impact.
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