鼻手术与咽手术治疗阻塞性睡眠呼吸暂停的比较

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Journal of Mind and Medical Sciences Pub Date : 2022-10-23 DOI:10.22543/2392-7674.1347
Ruxandra Oana Alius, V. Zainea, Cătălina Voiosu, I. Ioniță, A. Rusescu, O. Bălălău, Cătălin Aliuș, Raluca Oana Pulpa, R. Hainăroșie
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引用次数: 0

摘要

现代社会肥胖和不健康行为的地方性传播导致人们重新审视与阻塞性睡眠呼吸暂停相关的真实患病率。最近的数据支持了向个性化治疗的范式转变,其中包括上呼吸道的功能性手术。本文介绍了一项针对68名阻塞性睡眠呼吸暂停全科医生转诊患者的随机介入前瞻性研究结果。符合条件的队列包括28名患者,他们接受了功能性手术以最终缓解阻塞性症状。在对阻塞部位进行地形诊断并对阻塞性睡眠呼吸暂停的严重程度进行分级后,将符合条件的患者随机分为鼻腔手术或咽部手术。在术前和术后三个月进行主观和客观测量。结果显示,功能性手术后AHI显著降低(超过50%),而接受鼻腔手术治疗的患者获益甚微。两种手术方法的功能改善都是明确的,但鼻腔手术组报告的优越结果可能与研究组的规模相对较小有关。一个更大的队列参与后续类似设计的研究可以证实这些结果。
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Nasal surgery versus pharyngeal surgery in the treatment of obstructive sleep apnea
The endemic spread of obesity and unhealthy behaviors of modern society led to revisiting the real prevalence related to obstructive sleep apnea. Recent data support a paradigm shift towards individually tailored treatments which include functional surgery of the upper airways. This paper presents the results of a randomized interventional, prospective study on 68 patients referred by the general practitioner for obstructive sleep apnea. The eligible cohort consisted of 28 patients who were offered functional surgery for definitive relief of obstructive symptoms. After topographic diagnosis of the obstruction site and grading of the severity of the obstructive sleep apnea, the eligible lot was randomized for either nasal surgery or pharyngeal surgery. Subjective and objective measurements were carried out at presentation and three months after surgery. Results showed a significant reduction in AHI (more than 50%) after functional surgery, with marginal benefit for those treated with nasal surgery. Functional improvement is unequivocal for both surgical methods, but the superior results reported in the nasal surgery group could be related to the relatively small size of the study group. The involvement of a larger cohort in subsequent studies with a similar design could confirm these results.
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来源期刊
Journal of Mind and Medical Sciences
Journal of Mind and Medical Sciences MEDICINE, GENERAL & INTERNAL-
自引率
61.10%
发文量
37
审稿时长
8 weeks
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