Using of Saccharomyces Cerevisiae and Lactobacillus Acidophilus as Probiotic Against Salmonella Enterica Serovar Typhimurium Isolated from Poultry

The study aimed to determine the effect of S. cerevisiae and L. acidophilus as probiotic against S. typhimurium isolated from poultry, for this purpose (50) fecal samples were collected from poultry to isolated S. typhimurium, while fermented milk used for isolation of Lactobacillus acidophilus. Results of current study showed that S. typhimurium isolated in rate of 6%. In-Vivo adhesion Index test showed high ability of L. acidophilus to adhesion on rat intestine endothelium in compare with Saccharomyces cerevisiae .The inhibitory zone occurred by S.cerevisiae filtrate, L. acidophilus filtrate, (S .cerevisiae and L. acidophilus mixture) filtrate were (10, 16, 19 mm) respectively. The results of experimental study showed that high activity of (S.cerevisiae and L. acidophilus mixture) filtrate in protect experimental animals. Main pathological changes occurred by S.typhimurium were infiltration of inflammatory cells.