A. Maisarah, Suharni Mohamad, Maruzairi Husain, Sarimah Abdullah, R. Noordin
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引用次数: 0
摘要
弓形虫病是世界上最流行的人畜共患病之一。病原体，刚地弓形虫(Nicolle et Manceaux, 1908)是一种兼性异源、多源的顶复合体原生生物。在宿主物种内部和物种之间有几种潜在的传播途径。大多数弓形虫感染是由于与宠物/猫密切接触、食用受感染动物未煮熟的肉中的组织囊肿，以及从被猫粪便污染的食物或水中获得卵囊造成的。近年来，流行病学研究表明，弓形虫感染在多种精神疾病的发病机制中起着突出作用。本报告综述了弓形虫感染与精神疾病，特别是精神分裂症、抑郁症和双相情感障碍患者之间的关系。
Association between infection with Toxoplasma gondii and psychiatric disorders.
Toxoplasmosis is one of the world's most prevalent zoonoses. The causative agent, Toxoplasma gondii (Nicolle et Manceaux, 1908) is a facultative heteroxenic, polyxenic apicomplexan protist. There are several potential pathways of transmission within and between host species. Most infections with T. gondii result from close contact with pets/cats, ingestion of tissue cysts in undercooked meat of infected animals, and oocysts from food or water contaminated by feline faeces. Recently, epidemiological studies have shown that T. gondii infection plays a prominent role in the pathogenesis of several psychiatric disorders. This report reviews the association between T. gondii infection and patients with psychiatric disorders, particularly schizophrenia, depressive disorders and bipolar disorders.
期刊介绍：
FOLIA PARASITOLOGICA, issued in online versions, is an international journal that covers the whole field of general, systematic, ecological and experimental parasitology. It publishes original research papers, research notes and review articles. Contributions from all branches of animal parasitology, such as morphology, taxonomy, biology, biochemistry, physiology, immunology, molecular biology and evolution of parasites, and host-parasite relationships, are eligible. Novelty and importance in the international (not local or regional) context are required. New geographical records of parasites, records of new hosts, regional parasite and/or host surveys (if they constitute the principal substance of manuscript), local/regional prevalence surveys of diseases, local/regional studies on epidemiology of well known diseases and of parasite impact on human/animal health, case reports, routine clinical studies and testing of established diagnostic or treatment procedures, will not be considered. One species description will also not be considered unless they include more general information, such as new diagnostic characters, host-parasite associations, phylogenetic implications, etc. Manuscripts found suitable on submission will be reviewed by at least two reviewers.
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