β-葡聚糖在过敏中的作用

Sima Petr, V. Vaclav
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引用次数: 4

摘要

β-葡聚糖的多种作用已得到充分证实。葡聚糖与抗菌和抗癌免疫的作用一起,已被证明可以刺激骨髓细胞,降低胆固醇,防止压力和某些中毒。然而,尽管有数千篇论文描述了β-葡聚糖的生物学作用,但对β-葡聚糖在过敏反应中的作用的关注有限。我们的综述重点是评估目前对β-葡聚糖在过敏反应中可能作用的认识。大多数已发表的研究一致认为,基于Th1/Th2平衡的改善,β-葡聚糖显示出作为过敏患者标准治疗的辅助药物的发展潜力。
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β-Glucan in Allergies
Multiple effects of β-glucan are well established. Together with the effects on antibacterial and anticancer immunity, glucan has been shown to stimulate bone marrow cells, lower cholesterol and to protects against stress and some kinds of poisoning. However, despite literally thousands of papers describing biological effects of β-glucan, only limited attention has been focused on the role of β-glucan in allergic reactions. Our review is focused on evaluating the current knowledge of the possible role of β-glucan in allergic reactions. Most of published studies concur that based on the improved Th1/Th2 balance, β-glucan showed a potential for development as an adjunct to the standard treatment of in patients with allergies.
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