IgA vasculitis associated with renal and joint findings in children and correlation between patient’s compliance in treatment: A case series

Objectives. Evaluation and therapeutic management of pediatric patients having Henoch-Schönlein purpura with renal and joint involvement and the importance of their follow-up in preventing complications. Material and Methods: The present study follows cases of two patients, diagnosed with Henoch-Schönlein purpura, with different degrees of compliance, in which the therapeutic approach was determined by the severity of the patient’s conditions. Outcomes. Two male children with Henoch-Schönlein purpura, aged 11 and 9, shared the same clinical features, including skin lesions and joint involvement. The first case may be distinguished from the second one, due to renal injury, a significantly worsen general condition, more widespread purpura, and lower treatment conformity. Laboratory analyses revealed elevated D-Dimers between inflammatory markers, therefore corticotherapy and anticoagulants were initiated. Under the prescribed treatment, both children’s shapes improved, but the first one decided to be discharged on request before being fully recovered. Conclusions. In addition to symptomatic treatment, leisure, corticotherapy administration, and monitoring levels in blood pressure and renal function, patient compliance is highly important related to the prevention of chronic kidney disease at a later stage.