IgA血管炎与儿童肾脏和关节表现相关以及患者治疗依从性之间的相关性:一系列病例

Q4 Medicine Revista Romana de Pediatrie Pub Date : 2023-06-30 DOI:10.37897/rjp.2023.2.2
Ana-Maria Roxana Koller, Alexandra Man, C. Muntean
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引用次数: 0

摘要

目标。儿童过敏性紫癜合并肾脏和关节受累患者的评估和治疗管理,以及随访对预防并发症的重要性。材料和方法:本研究随访了两例诊断为过敏性紫癜的患者,他们有不同程度的依从性,其中治疗方法由患者病情的严重程度决定。结果。两名患有过敏性紫癜的男性儿童,年龄分别为11岁和9岁,具有相同的临床特征,包括皮肤病变和关节受累。第一种情况可能与第二种情况不同,因为肾损伤、一般情况明显恶化、紫癜更广泛、治疗依从性较低。实验室分析显示,炎症标志物之间的D-二聚体升高,因此开始使用皮质类固醇治疗和抗凝剂。在规定的治疗下,两个孩子的体型都有所改善,但第一个孩子决定在完全康复前应要求出院。结论。除了症状治疗、休闲、皮质类固醇治疗以及监测血压和肾功能水平外,患者的依从性与后期慢性肾脏疾病的预防非常重要。
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IgA vasculitis associated with renal and joint findings in children and correlation between patient’s compliance in treatment: A case series
Objectives. Evaluation and therapeutic management of pediatric patients having Henoch-Schönlein purpura with renal and joint involvement and the importance of their follow-up in preventing complications. Material and Methods: The present study follows cases of two patients, diagnosed with Henoch-Schönlein purpura, with different degrees of compliance, in which the therapeutic approach was determined by the severity of the patient’s conditions. Outcomes. Two male children with Henoch-Schönlein purpura, aged 11 and 9, shared the same clinical features, including skin lesions and joint involvement. The first case may be distinguished from the second one, due to renal injury, a significantly worsen general condition, more widespread purpura, and lower treatment conformity. Laboratory analyses revealed elevated D-Dimers between inflammatory markers, therefore corticotherapy and anticoagulants were initiated. Under the prescribed treatment, both children’s shapes improved, but the first one decided to be discharged on request before being fully recovered. Conclusions. In addition to symptomatic treatment, leisure, corticotherapy administration, and monitoring levels in blood pressure and renal function, patient compliance is highly important related to the prevention of chronic kidney disease at a later stage.
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CiteScore
0.10
自引率
0.00%
发文量
15
审稿时长
4 weeks
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