经颅磁疗联合电刺激治疗肥胖男孩神经内分泌免疫功能紊乱

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Russian Open Medical Journal Pub Date : 2022-03-20 DOI:10.15275/rusomj.2022.0111
N. Bolotova, N. Filina, M. S. Kurdiyan, O. Kompaniets, L. Garifulina, Irina Yu. Meshcheryakova
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引用次数: 1

摘要

目的:证明低强度经颅磁疗法(TCMT)联合电刺激(TES)治疗神经内分泌免疫障碍的合理性。材料与方法——对50名13~15岁的外源性体质性肥胖男孩进行了调查。对照组由30名13-15岁的男孩组成,他们没有肥胖和伴随的病理。检查包括对主诉、疾病记忆、生活史、客观数据、激素状态、神经递质和细胞因子的评估。通过随机抽样,肥胖儿童组被分为两个亚组:1a亚组(n=24),接受TCMT联合TES治疗,1b亚组-对照组(n=22),接受安慰剂治疗,电极断开。两组儿童都收到了相同的营养建议。3个月后对治疗效果进行评估。治疗过程包括10个步骤。使用统计软件包Statistica 8对所获得的数据进行统计处理。结果——在TCMT联合TES的影响下,1a亚组(n=24)的儿童睾酮和β-内啡肽水平升高,雌二醇和kisspeptin水平下降,同时体重下降。在接受电极断开的安慰剂治疗的1b亚组(n=22)中,体重也有所下降,但水平要低得多。结论:TCMT与TES联合使用可使神经内分泌免疫紊乱正常化,并有助于减肥。
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Using Transcranial Magnetic Therapy In Combination With Electrostimulation For Correcting Neuroendocrine-Immune Disorders In Obese Boys
Objective — To justify the use of low-intensity transcranial magnetic therapy (TCMT) in combination with electrostimulation (TES) for the correction of neuroendocrine-immune disorders. Material and Methods — Fifty adolescent boys with exogenous constitutional obesity 13-15 years of age were examined. The control group consisted of 30 boys aged 13-15 years without obesity and concomitant pathology. The examination included an assessment of complaints, anamnesis of the disease, life history, objective data, hormonal status, neurotransmitters and cytokines. By random sampling, the group of obese children was divided into two subgroups: subgroup 1a (n=24), who received TCMT in combination with TES, and subgroup 1b – comparison group (n=22), who received placebo therapy with disconnected electrodes. Both groups of children received identical recommendations regarding the nutrition. The effectiveness of the therapy was evaluated after 3 months. The treatment course comprised 10 procedures. Statistical processing of the obtained data was carried out using the statistical software package Statistica 8. Results — An increase in the levels of testosterone and β – endorphin as well as a decrease in estradiol and kisspeptin, which was accompanied by a decrease in body weight was observed in children of subgroup 1a (n=24) under the influence of TCMT in combination with TES. In subgroup 1b (n=22) receiving placebo therapy with disconnected electrodes, there was also a decrease in body weight, but at a much lower level. Conclusion — The use of TCMT in combination with TES led to the normalization of neuroendocrine-immune disorders and contributed to weight loss.
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来源期刊
Russian Open Medical Journal
Russian Open Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
39
期刊介绍: Russian Open Medical Journal (RusOMJ) (ISSN 2304-3415) is an international peer reviewed open access e-journal. The website is updated quarterly with the RusOMJ’s latest original research, clinical studies, case reports, reviews, news, and comment articles. This Journal devoted to all field of medicine. All the RusOMJ’s articles are published in full on www.romj.org with open access and no limits on word counts. Our mission is to lead the debate on health and to engage, inform, and stimulate doctors, researchers, and other health professionals in ways that will improve outcomes for patients. The RusOMJ team is based mainly in Saratov (Russia), although we also have editors elsewhere in Russian and in other countries.
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