慢性丙型肝炎病毒感染1b亚型患者皮肤胶原血管病变1例

Q4 Medicine Vestnik dermatologii i venerologii Pub Date : 2022-11-01 DOI:10.25208/vdv1343
Rada Shpiluyk, I. Belousova, D. Sulima, Safura Sulejmanova, Y. Gorbunov, Natalia Blum
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引用次数: 0

摘要

本文研究了一种罕见的皮肤胶原血管病变(CCV),其特征是常见的皮革毛细血管扩张和特殊的组织学征象:真皮表层毛细血管扩张,其壁因含有IV型胶原的透明沉积而增厚。根据文献资料,在俄文资料中没有关于CCV的出版物。在国外文献中,只有60例被描述,其中第一例是在2000年被提到的。患者为解决慢性hcv感染1b亚型的治疗策略问题及双巩膜皮肤和粘膜常见毛细血管扩张的主诉,无主观感觉,转至EXCLUSIVE医疗诊所。第一次皮疹出现在2008年,并逐渐恶化。组织学检查发现真皮表层毛细血管扩张,由于含有IV型胶原蛋白的蛋白质沉积,毛细血管壁增厚。所描述的CCV病例是俄罗斯文献中的第一例,表明需要进行组织学和免疫组织学研究以确定最终诊断。
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Rare case of cutaneous collagenous vasculopathyin a patient with chronic HCV infection 1b subtype
The article is devoted to a rare disease of cutaneous collagenous vasculopathy (CCV), which is characterized by common leather telangiectasias and specific histological signs: extended capillaries in the surface layers of the dermis, the walls of which are thickened due to hyaline deposits containing type IV collagen. According to literature, there are no publications about CCV in Russian sources. In foreign literature, only 60 cases are described, the first of which is mentioned in 2000. The patient turned to the EXCLUSIVE medical clinic to resolve the issue of the tactics of treatment of chronic HCV-infection 1b subtype and complaints of common telangiectasia on the skin and mucous membrane of both sclera, without subjective sensations. The first rashes appeared in 2008 and gradually progressed. When performing histological examination, expanded capillaries were found in the surface layers of the dermis, the walls of which are thickened due to protein deposits containing type IV collagen. The described case of CCV is the first in Russian literature and shows the need for histological and immunohistologycal studies to establish a final diagnosis.
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
40
审稿时长
8 weeks
期刊最新文献
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