甘油愈创木酚醚对行睾丸切除术马站立时的镇静作用

IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Arquivo Brasileiro De Medicina Veterinaria E Zootecnia Pub Date : 2023-06-01 DOI:10.1590/1678-4162-12912
R. S. Tramontin, R. B. Zavilenski, S. S. Calomeno, G.H.M. Navarro, S. T. Belettini, A. Leitzke, T. B. Borges, R.G.D’O.C. Vilani, A. M. Quessada
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引用次数: 0

摘要

摘要:一项研究旨在比较两种镇静方案,用于站立时接受睾丸切除术的马。在这两个方案中,通过静脉注射(IV)使用剂量为10µg/kg的脱毒脒来诱导进入镇静状态。在第一个方案(八匹马)中,持续输注1%甘油愈创木酚醚(GGE)以1ml/kg/小时IV的剂量维持镇静状态。对所有动物进行了睾丸切除术。这两个方案允许在站立时进行手术。然而,被GGE保持镇静的马表现出更大的放松和更强烈的镇静程度。需要注意的是,使用GGE来维持马的镇静状态在文献中是前所未有的。该药物用于该物种的麻醉方案,但仅用于全身麻醉中的麻醉前药物。得出的结论是,这两种镇静方案允许在站立时对马进行睾丸切除术。然而,使用1%GGE的方案显示出更深刻的镇静作用,没有副作用。
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Glyceryl guaiacol ether for sedation of horses undergoing orchiectomy when standing
ABSTRACT A study was designed to compare two sedation protocols to be used in horses undergoing orchiectomy when standing. In both protocols, the induction to the sedative state was performed with bolus detomidine at a dose of 10 µg/kg, intravenously (IV). In the first protocol (eight horses), the sedative state was maintained with 1% glyceryl guaiacol ether (GGE) in continuous infusion, at a dose of 1ml/kg/hour IV. In the second protocol (eight horses) this sedative effect was maintained with detomidine in continuous infusion at the same dose and induction route. Orchiectomy was performed on all animals. The two protocols allowed the surgeries to be performed when standing. However, horses kept under sedation by the GGE showed greater relaxation and a more intense degree of sedation. It should be noted that the use of GGE to maintain the sedative state in horses is unprecedented in the literature. The drug is used in anesthetic protocols in the species, but only in pre-anesthetic medication in general anesthesia. It was concluded that the two sedation protocols allowed the performance of orchiectomy with the horses when standing. However, the protocol in which 1% GGE was used showed more profound sedation, without adverse effects.
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来源期刊
CiteScore
0.80
自引率
25.00%
发文量
111
审稿时长
9-18 weeks
期刊介绍: Publica artigos originais de pesquisa sobre temas de medicina veterinária, zootecnia, tecnologia e inspeção de produtos de origem animal e áreas afins relacionadas com a produção animal. Atualmente a revista mantém 628 permutas (419 internacionais e 209 nacionais), sendo um verdadeiro suporte para o recebimento de periódicos pela Biblioteca da Escola. A partir de 1999, a Escola de Veterinária delegou à FEP MVZ Editora o encargo do gerenciamento e edição de todas suas publicações, inclusive do Arquivo, ficando somente com o apoio logístico (instalações, equipamentos, pessoal etc.). O apoio financeiro é exercido pelo CNPq/FINEP e pela própria FEP MVZ.
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