生物玻璃和羟基磷灰石填充支架的制备和表征。

Laura Mendoza-Cerezo, J. Rodríguez-Rego, Anabel Soriano-Carrera, Alfonso C. Marcos-Romero, A. Macías-García
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引用次数: 0

摘要

组织工程是一个不断发展的领域。该领域的主要研究方向之一集中在用设计成与活体细胞相互作用的材料替换骨缺损,以便为身体提供一种新组织可以容易生长的结构。生物玻璃是最常用的材料之一,由于其多功能性和良好的性能而经常使用。本文讨论了使用热塑性塑料(PLA)通过增材制造在3D打印多孔结构上生产Bioglass®45S5和羟基磷灰石的可注射糊状物的结果。该结果在该糊剂的特定应用中进行了评估,因此对其机械和生物活性进行了研究,以表明将该组合用于再生医学,更具体地说,用于骨植入物的多种可能性。
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Fabrication and characterisation of bioglass and hydroxyapatite-filled scaffolds.
Tissue engineering is a continuously evolving field. One of the main lines of research in this field focuses on the replacement of bone defects with materials designed to interact with the cells of a living organism in order to provide the body with a structure on which new tissues can easily grow. Among the most commonly used materials are bioglasses, which are frequently used due to their versatility and good properties. This article discusses the results of the production of an injectable paste of Bioglass® 45S5 and hydroxyapatite on a 3D printed porous structure by additive manufacturing, using a thermoplastic (PLA). The results were evaluated in a specific application of the paste, so the mechanical and bioactive properties were studied to show the multiple possibilities of using this combination for its application in regenerative medicine and more specifically in bone implants.
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