颗粒物在皮肤炎症中的作用

Q4 Immunology and Microbiology Journal of Bacteriology and Virology Pub Date : 2019-06-01 DOI:10.4167/JBV.2019.49.2.89
Madeeha Arooj, Y. Koh
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引用次数: 1

摘要

©这是一篇根据知识共享署名非商业许可条款分发的开放获取文章(http://creativecommons.org/license/bync/3.0/)。环境污染是影响人类健康的一个重大全球问题。在不同类型的环境污染中,颗粒物(PM)起着关键作用。当PM在空气中传播时,它会引起不同的支气管和皮肤炎症。PM通过产生ROS和促炎细胞因子增加氧化应激。结果,还产生基质金属蛋白酶,如MMP1、MMP9和MMP2,这是已知的皮肤胶原降解的主要原因。最近有研究表明,PM会加重过敏性疾病,如皮炎、牛皮癣和皮肤癌症。为了控制这一PM,全球范围内已经做出了不同的广泛努力。
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Role of Particulate Matter in Skin Inflammation
©This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ license/by-nc/3.0/). Environmental pollution is a major global problem that affects human health. Among different types of environmental pollution, particulate matter (PM) has a key role. As PM spreads in the air so it causes different bronchial and skin inflammatory conditions. PM increases oxidative stress by ROS production and pro-inflammatory cytokines. As a result, matrix metalloproteinase is also produced, such as MMP1, MMP9 and MMP2 that is a known major cause of skin collagen degradation. Recently it has been shown that the PM worsens allergic conditions like dermatitis, psoriasis, and skin cancer. Different extensive efforts have been made across the globe to control this PM.
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来源期刊
Journal of Bacteriology and Virology
Journal of Bacteriology and Virology Immunology and Microbiology-Immunology
CiteScore
0.80
自引率
0.00%
发文量
16
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