古绢兰粗醇提物和水提物的抗微生物活性、血凝活性和植物毒性

IF 2 4区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Journal of Traditional Chinese Medicine Pub Date : 2018-06-01 DOI:10.1016/S0254-6272(18)30635-6
Kafeel Ahmad, Amjad Ali, Waqar Ahmed Afridi, Ramla Somayya, Muhammad Jawad Ullah
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引用次数: 8

摘要

目的研究古绢兰粗醇提物和水提物的抑菌活性、血凝活性和植物毒性。方法采用琼脂孔扩散法对金黄色葡萄球菌、耐甲氧西林金黄色葡萄球菌、大肠埃希菌、肺炎克雷伯菌、枯草芽孢杆菌和伤寒沙门菌5种细菌进行检测。并用琼脂管扩散法对6种真菌——黑曲霉、黄曲霉、茄疫病菌、茄根丝核菌、茄枯萎菌和佛罗里达侧耳菇进行了抑菌筛选。此外,还评估了粗乙醇提取物和水提取物的血凝活性和植物毒性活性。结果乙醇粗提物和水提物对真菌和细菌的抑制作用呈剂量依赖性。未观察到血凝活性。乙醇提取物和水提取物对小檗碱均表现出剂量依赖性的植物毒活性。结论古绢金的乙醇粗提物和水提物具有良好的抗微生物活性和植物毒性,但无血凝活性。
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Antimicrobial, hemagglutination and phytotoxic activity of crude ethanolic and aqueous extracts of Seriphidium kurramense

OBJECTIVE

To investigate the antimicrobial activity, hemagglutination and phytotoxic activity of crude ethanolic and aqueous extracts of Seriphidium kurramense.

METHODS

The extracts were analyzed by agar well diffusion assays against five bacterial species: Staphylococcus aureus (S. aureus), methicillin-resistant S. aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis, and Salmonella typhi. The extracts were also screened against six fungal species — Aspergillus niger, Aspergillus flavus, Alternaria solani, Rhizoctonia solani, Fusarium solani and Pleurotus florida — using the agar tube diffusion method. Additionally, hemagglutination and phytotoxic activities of the crude ethanolic and aqueous extracts were assessed.

RESULTS

The crude ethanolic and aqueous extracts showed dose-dependent inhibition of the various tested fungal and bacterial strains. No hemagglutination activity was observed. Both the ethanolic and aqueous extracts showed dose-dependent phytotoxic activity toward Lemna minor.

CONCLUSION

The crude ethanolic and aqueous extracts of Seriphidium kurramense possess good antimicrobial and phytotoxic activities, but no hemagglutination activity.

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来源期刊
Journal of Traditional Chinese Medicine
Journal of Traditional Chinese Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
2.40
自引率
3.80%
发文量
32269
审稿时长
2 months
期刊介绍: Journal of Traditional Chinese Medicine(JTCM) is devoted to clinical and theortical research on the use of acupuncture and Oriental medicine. The main columns include Clinical Observations, Basic Investigations, Reviews, Questions and Answers, an Expert''s Forum, and Discussions of Clinical Cases. Its key topics include acupuncture and electro-acupuncture, herbal medicine, homeopathy, masseotherapy, mind-body therapies, palliative care, and other CAM therapies.
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