尼泊尔东部三级医疗中心就诊人群维生素D状况的医院研究

C. P. Gaire
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引用次数: 0

摘要

背景:维生素D缺乏是世界范围内严重的健康问题,其血浆浓度的估计是至关重要的。该研究旨在确定在尼泊尔东部三级保健中心之一比拉特医学院教学医院就诊的患者体内维生素D的循环水平。材料与方法:在尼泊尔比拉特医学院教学医院生物化学系进行描述性横断面研究。从医院登记处检索了250名患者的临床数据,包括他们的年龄、性别和血清25-羟基维生素D,从2021年5月到8月的四个月。维生素D状态分为缺乏(<10 ng/mL)、不足(10 - 30ng/mL)、充足(≥30ng/mL)和毒性(≥100 ng/mL)。结果:在所有受试者中(n=250),没有人显示出维生素D的血清浓度有毒,38%的人维生素D充足,57%的人维生素D不足,5%的人维生素D缺乏。在受影响的人群中,41%的41-60岁人群以维生素D不足为主。维生素D不足组的性别对比显示,大约33%的男性和67%的女性维生素D不足。结论:由于超过一半的研究人群存在维生素D不足,因此进一步研究除年龄和性别外的相关因素变得至关重要。为此,需要进一步的研究。
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Status of Vitamin D among People Visiting a Tertiary Care Center of Eastern Nepal: A Hospital-Based Study
Background: Vitamin D deficiency is a serious health-problem worldwide and the estimation of its plasma concentration is crucial. The study aims to determine the circulating levels of vitamin D in patients visiting Birat Medical College Teaching Hospital, one of the tertiary care centers of Eastern Nepal. Materials and Methods: It was descriptive cross-sectional study conducted in the Department of Biochemistry at Birat Medical College Teaching Hospital, Nepal. From the hospital registry, clinical data of 250 patients including their age, gender and serum 25-hydroxy vitamin D was retrieved for the four months of May – August, 2021. The vitamin D status was classified as deficiency (<10 ng/mL), insufficiency (10–30ng/mL), sufficiency ≥ 30ng/mL) and toxicity (≥ 100 ng/mL). Results: Out of total subjects (n=250), none of them showed toxic serum concentrations of vitamin D, 38% had sufficient, 57% had insufficient and 5% had deficient levels of this vitamin. Among affected individuals, vitamin D insufficiency had predominated in 41% population who were 41-60 years old. Gender-wise comparison of vitamin D status in the insufficiency group showed around 33% males and 67% females having insufficient levels of this vitamin. Conclusion: With the vitmain D inssufficieny present in more than half of the study population, it becomes paramount to further scrutinize the associated factors apart from the age and gender. To this end, further studies are needed.  
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