li Reza Molla Ebrahimlo, Mounes Hanaforoush, Roya Attari
{"title":"甘氨酸-盐酸缓冲液为溶剂和生物催化剂，采用Hantzsch反应高效、环保地合成1,4 -二氢吡啶","authors":"li Reza Molla Ebrahimlo, Mounes Hanaforoush, Roya Attari","doi":"10.25135/ACG.OC.58.19.05.1273","DOIUrl":null,"url":null,"abstract":"A green and efficient procedure was established to synthesize 1,4-dihydropyridines via one-pot Hantzsch reactions in buffering conditions without the use of organic solvent. In this method, Glycine-HCl buffer solution was used as solvent and catalyst reaction; therefore, using this method has several benefits including high yields, an environmentally friendly procedure, short reaction times, and a simple work-up procedure. All the compounds were characterized by TLC, FT-IR, H NMR and elemental studies.","PeriodicalId":19553,"journal":{"name":"Organic Communications","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2019-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"An efficient and eco-friendly synthesis of 1, 4-dihydropyridines via Hantzsch reaction in Glycine-HCl buffer as solvent and bio-catalyst\",\"authors\":\"li Reza Molla Ebrahimlo, Mounes Hanaforoush, Roya Attari\",\"doi\":\"10.25135/ACG.OC.58.19.05.1273\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A green and efficient procedure was established to synthesize 1,4-dihydropyridines via one-pot Hantzsch reactions in buffering conditions without the use of organic solvent. In this method, Glycine-HCl buffer solution was used as solvent and catalyst reaction; therefore, using this method has several benefits including high yields, an environmentally friendly procedure, short reaction times, and a simple work-up procedure. All the compounds were characterized by TLC, FT-IR, H NMR and elemental studies.\",\"PeriodicalId\":19553,\"journal\":{\"name\":\"Organic Communications\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2019-06-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic Communications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25135/ACG.OC.58.19.05.1273\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25135/ACG.OC.58.19.05.1273","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
An efficient and eco-friendly synthesis of 1, 4-dihydropyridines via Hantzsch reaction in Glycine-HCl buffer as solvent and bio-catalyst
A green and efficient procedure was established to synthesize 1,4-dihydropyridines via one-pot Hantzsch reactions in buffering conditions without the use of organic solvent. In this method, Glycine-HCl buffer solution was used as solvent and catalyst reaction; therefore, using this method has several benefits including high yields, an environmentally friendly procedure, short reaction times, and a simple work-up procedure. All the compounds were characterized by TLC, FT-IR, H NMR and elemental studies.
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