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引用次数: 0
摘要
20世纪50年代,安东尼·林奈(Anthony Linnane)在悉尼大学(University of Sydney)攻读博士学位期间,从面包师的酵母中分离出线粒体。随后,在20多年的时间里,直到20世纪80年代中期,他率先研究了线粒体的生物发生,包括酶学、膜生物化学、分子生物学和遗传学。这些发现主要是在莫纳什大学完成的,并为他赢得了联邦航空队(1972年)和联邦航空队(1980年)的选举。此后,林奈将他的研究扩展到医学领域,特别是线粒体在人类衰老中的作用,以及对干扰素和癌症特异性黏液抗原的研究。1996年从莫纳什大学退休后,林奈在墨尔本的分子生物学和医学中心工作,致力于通过生物能源策略改善疾病。他在澳大利亚生物化学学会和国际生物化学联合会发挥了重要作用。
Anthony (Tony) Linnane isolated mitochondria from bakers’ yeast during his doctoral studies at the University of Sydney in the 1950s. He subsequently pioneered research into the biogenesis of mitochondria, covering enzymology, membrane biochemistry, and molecular biology and genetics, over more than two decades until the mid-1980s. These discoveries were made mostly at Monash University and earned him election as FAA (1972) and FRS (1980). Linnane thereafter broadened his research towards medical topics, especially the role of mitochondria in human ageing, together with studies on interferon and cancer-specific mucinous antigens. After retirement from Monash in 1996, Linnane worked towards ameliorating disease through bioenergetic strategies, based at the Centre for Molecular Biology and Medicine in Melbourne. He played significant roles in the Australian Biochemical Society and the International Union of Biochemistry.
期刊介绍:
Historical Records of Australian Science is a bi-annual journal that publishes two kinds of unsolicited manuscripts relating to the history of science, pure and applied, in Australia, New Zealand and the southwest Pacific.
Historical Articles–original scholarly pieces of peer-reviewed research
Historical Documents–either hitherto unpublished or obscurely published primary sources, along with a peer-reviewed scholarly introduction.
The first issue of the journal (under the title Records of the Australian Academy of Science), appeared in 1966, and the current name was adopted in 1980.