双相情感障碍患者前瞻性记忆与气质的关系

Qing Wu, Ying Wang, Haining Yu
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摘要

目的探讨基于事件的前瞻性记忆(EBPM)和基于时间的前瞻性记忆力(TBPM)在双相情感障碍患者中的作用,探讨前瞻性记忆与气质的关系。方法选择50例处女膜双相情感障碍患者(病例组)和45例人口统计学特征匹配的健康对照组(对照组)。使用包括EBPM和TBPM任务在内的神经心理学测试组来测量前瞻性记忆,所有参与者都完成了记忆者的中文版短期气质评估(TEMPS-A)。用t检验比较病例组和对照组在前瞻性记忆和气质方面的差异。采用Pearson相关分析法分析了前瞻性记忆与气质的相关性。结果双相情感障碍患者的EBPM与健康对照组比较有统计学意义((3.66±0.69)vs(4.18±0.83),t=-3.313,P<0.01),TBPM与正常对照组比较((3.06±0.96)vs(3.89±0.75),t=-4.674,P<0.01),P<0.01),病例组各分量表得分均高于对照组。病例组抑郁气质评分与TBPM呈负相关(r=-0.425,P=0.002)。结论在双相情感障碍患者中,EBPM和TBPM均有损害,且TBPM与抑郁气质适度相关。关键词:双相情感障碍;前瞻性记忆;气质
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Relationship between prospective memory and temperament in patients with euthymic bipolar disorder
Objective To investigate the event-based prospective memory(EBPM) and time-based prospective memory(TBPM) in patients with euthymic bipolar disorder and to explore the relationships between prospective memory and temperament. Methods Fifty patients with euthymic bipolar disorder(case group) and forty-five demographic characteristic matched healthy controls(control group) were recruited.The neuropsychological battery of tests including EBPM and TBPM tasks were used to measured the prospective memory, and all participants completed the Chinese version of short temperament evaluation of the memphis(TEMPS-A). The differences in prospective memory and temperament between the case group and control group were compared by t test.Pearson correlation analysis was used to analyze the correlation between prospective memory and temperament. Results A statistically significant in EBPM was observed between patients with euthymic bipolar disorder and health controls ((3.66±0.69) vs (4.18±0.83), t=-3.313, P<0.01) and the same result was showed in TBPM ((3.06±0.96) vs (3.89±0.75), t=-4.674, P<0.01). The total score of TEMPS-A ((18.82±4.49) vs (9.69±3.37), t=11.106, P<0.01) and the scores of all the subscales were higher in case group than those in control group.The negative correlation was showed between the scores of depression temperament and TBPM (r=-0.425, P=0.002) in the case group. Conclusion The results suggest both EBPM and TBPM have impaired, and TBPM correlates with depression temperament moderately in the patients with euthymic bipolar disorder. Key words: Bipolar disorder; Prospective memory; Temperament
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期刊介绍: "Chinese Journal of Behavioral Medicine and Brain Science" (CN 37-1468/R, ISSN 1674-6554) is a national academic journal under the supervision of the National Health Commission, sponsored by the Chinese Medical Association and Jining Medical College. The journal was founded in June 1992 and was formerly known as "Chinese Journal of Behavioral Medicine" (1992-1993) and "Chinese Behavioral Medical Science" (1994-2008). In 2009, it was renamed "Chinese Journal of Behavioral Medicine and Brain Science" with the approval of the State Administration of Press, Publication, Radio, Film and Television. The purpose of "Chinese Journal of Behavioral Medicine and Brain Science" is to implement the health and health policies of the Party and the State, implement the principle of combining theory with practice and popularization and improvement, and reflect the major progress in the theory and practical application of behavioral medicine and brain science in my country. It publishes academic papers and scientific research results in the field of behavioral medicine and brain science in my country, and has columns such as monographs/reviews, basic research, clinical research, health prevention, methods and techniques, psychological behavior and evaluation, and systematic evaluation.
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