手性分离中对映体选择性萃取的研究进展

M. Hashemi, Hadjmohammadi Mr
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引用次数: 0

摘要

本文讨论了近年来对映选择性提取方法的发展。这个领域有几种方法。介绍了所有对映选择性提取方法的原理,重点介绍了两相提取,在这些方法中使用了一种手性化合物,称为手性选择器,该化合物在络合过程中区分了两种手性异构体,然后一种异构体被手性选择器捕获,并发生分离过程。手性选择子应在相中溶解。在这些方法中,典型的性能数据主要集中在分布比和对映选择性值或选择性因子上。本文介绍了几种对映选择性提取方法,并结合实例进行了讨论。
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Recent Development: Enantioselective Extraction in Chiral Separation
This paper discusses the recent development of enantioselective extraction methods. There are several methods in this field. The principles of all of enantioselective extraction methods are presented a focus on twophase extractions, in these methods used a chiral compound that named chiral selector, this compound distinguishes between two chiral isomers in complexation process, then one isomer more captured by chiral selector, and separation processes happen. The chiral selector should dissolve in on phase. In these methods, typical performance data are reported major emphasis on distribution ratio and enantioselectivity value or selectivity factor. In this paper, we introduce types of enantioselective extraction method, and discuss about them with several examples.
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