股骨远端骨旁骨肉瘤半皮质切除和同种异体骨移植生物重建后的肿瘤和功能结果

Q2 Medicine Sarcoma Pub Date : 2022-06-02 DOI:10.1155/2022/5153924
O. Savvidou, Stavros D Goumenos, Ioannis G. Trikoupis, A. Kaspiris, Dimitra Melissaridou, P. Gavriil, J. Georgoulis, P. Papagelopoulos
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摘要

腮腺骨肉瘤(PAOS)是一种表面骨肉瘤。治疗选择包括广泛切除和内修复或同种异体移植物。然而,由于局部复发和转移率较低,当病变出现在股骨远端后表面时,可以通过半皮质广泛切除和半皮质同种异体移植物生物重建来治疗。本研究的目的是评估股骨远端后皮质骨旁骨肉瘤(PAOS)患者在半皮质切除后进行生物重建的肿瘤学和功能结果。方法回顾性分析11例应用半皮质同种异体骨移植行股骨远端大面积肿瘤切除和缺损重建的患者。使用肌肉骨骼肿瘤学会(MSTS)评分系统评估局部复发、转移、并发症和功能结果。结果术后平均随访时间为53.64个月(30~84个月) 月)。在最近的随访中,所有患者都没有出现无转移的疾病迹象。1例局部复发患者接受了自体腓骨移植重建的翻修手术。MSTS平均得分为93.45 ± 3.56.结论采用半皮质切除和同种异体移植物重建治疗股骨远端后部PAOS患者具有满意的肿瘤学和功能结果,并发症发生率低。
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Oncological and Functional Outcomes after Hemicortical Resection and Biological Reconstruction Using Allograft for Parosteal Osteosarcoma of the Distal Femur
Background Parosteal osteosarcoma (PAOS) is a surface osteosarcoma. Treatment options include wide excision and endoprosthetic or allograft. However, due to the low local recurrence and metastasis rate, when it appears in the posterior surface of the distal femur, the lesion can be managed with hemicortical wide resection and biological reconstruction with hemicortical allograft. The purpose of this study is to evaluate the oncological and functional outcomes of patients with parosteal osteosarcoma (PAOS) of the posterior cortex of the distal femur who underwent biological reconstruction after hemicortical resection. Methods Eleven patients who underwent wide tumor resection and defect reconstruction of the posterior surface of the distal femur using hemicortical allograft were retrospectively studied. Local recurrence, metastasis, complications, and the functional outcome using the Musculoskeletal Tumor Society (MSTS) scoring system were evaluated. Results The average postoperative follow-up period was 53.64 months (range, 30 to 84 months). At the latest follow-up, all patients had no evidence of disease without metastases. One patient with local recurrence underwent revision surgery with fibula autograft reconstruction. The mean MSTS score was 93.45 ± 3.56. Conclusions Treatment of patients with PAOS of the posterior aspect of the distal femur with hemicortical resection and allograft reconstruction has satisfactory oncological and functional outcome and low complication rates.
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来源期刊
Sarcoma
Sarcoma Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
5.00
自引率
0.00%
发文量
15
审稿时长
14 weeks
期刊介绍: Sarcoma is dedicated to publishing papers covering all aspects of connective tissue oncology research. It brings together work from scientists and clinicians carrying out a broad range of research in this field, including the basic sciences, molecular biology and pathology and the clinical sciences of epidemiology, surgery, radiotherapy and chemotherapy. High-quality papers concerning the entire range of bone and soft tissue sarcomas in both adults and children, including Kaposi"s sarcoma, are published as well as preclinical and animal studies. This journal provides a central forum for the description of advances in diagnosis, assessment and treatment of this rarely seen, but often mismanaged, group of patients.
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